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White Blood Cells . Types Functions. phagocyte.ram. Neutrophils (Microphages) The first line of defense against bacterial infections. . Eosinophils Increase in : parasitic infections allergic diseases. Basophils liberate heparin and histamine. Monocytes (Macrophages)
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White Blood Cells Types Functions
Neutrophils(Microphages) The first line of defense against bacterial infections.
Eosinophils Increase in: parasitic infections allergic diseases.
Basophils liberate heparin and histamine.
Monocytes (Macrophages) The second line of defense against bacterial infection. They engulf and kill bacteria and Play an important role in immunity.
Lymphocytes are the major constituents of the immune system.
The Reticuloendothelial System (R.E.S.)Tissue Macrophage System Defense: The tissue macrophages attack and engulf the invading organisms in the: (a) Skin and subcutaneous tissue (histocytes) (b) Lungs (pulmonary alveolar macrophages). (c) Liver (Kupffer cells). (d) Lymph nodes. (e) Bone marrow and spleen.
Removal of all old blood cells. • Breakdown of Hb, formation of bile pigments and storage of iron. • Repair of damaged tissues after inflammation • Extramedullary hemopoiesis (in cases of sever bone marrow depression, and chronic hemolytic anemias). • The Kupffer cells form a small amount of erythropoietin.
Leucocytosis *Physiological leucocytosis: -Pregnancy -After a cold bath -Muscular exercise -Following meals -Emotions -Pain *Phathological leucocytosis: Neutrophilia: Infection (e.g. tonsillitis,…)Tissue damage (fracture, myocardial infarction,…) Eosinophilia: Allergic and Parasitic diseases Basophilia: allergic conditions Lymphocytosis: chronic infections (e.g. T.B.) Malignant leucocytosis: Leukemias
Leukopenia and Agranulocytosis • Causes: Bone marrow depression
Immunity It is the ability of the body to resist various microorganisms and toxins that tend to invade it and cause tissue destruction. Types: • Innate immunity. • Acquired immunity.
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