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Control Points of Gene Regulation

Control Points of Gene Regulation. Transcription. RNA Processing. DNA. RNA Transport. DNA. RNA Degradation. mRNA. 5’. process. 3’. ribosome. mature mRNA. Translation. mRNA. cap 5’. 3’ tail. Activity. proteins. Proteolysis. proteins. Prokaryotics. Post-translational

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Control Points of Gene Regulation

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  1. Control Points of Gene Regulation Transcription RNA Processing DNA RNA Transport DNA RNA Degradation mRNA 5’ process 3’ ribosome mature mRNA Translation mRNA cap 5’ 3’ tail Activity proteins Proteolysis proteins Prokaryotics Post-translational control Eukaryotics Juang RH (2004) BCbasics

  2. Regulation of Enzyme Activity Inhibitor Proteolysis or inhibitor Feedback regulation Phosophorylation P Signal transduction Regulatory subunit (-) proteolysis P R R (+) regulator effector phosphorylation or + cAMP or calmodulin Juang RH (2004) BCbasics

  3. Cascade Amplification of Signals 1 Enzyme nS nP Cascade Juang RH (2004) BCbasics

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