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L6172 Law and Social Science R eview. April 23, 2007. Daubert and the FREs. Daubert supplanted Frye Daubert – Medical/clinical research Joiner – Epidemiological research Kumho – Engineering U.S. v. Hall – Social science Parallel drift in FRE slightly earlier in time
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L6172 Law and Social ScienceReview April 23, 2007
Daubert and the FREs • Daubert supplanted Frye • Daubert – Medical/clinical research • Joiner – Epidemiological research • Kumho – Engineering • U.S. v. Hall – Social science • Parallel drift in FRE slightly earlier in time • Daubert emphasized method • Daubert increased procedural formality, imposed a “giving reasons” requirement on judges
Daubert in Action • Is Frye really dead? • Similar social forces that elevate particular methods to prominence and acceptability also produce “expertise” that Frye rules emphasized • Daubert reifies the authority of scientific gatekeepers, as well as judicial gatekeepers • Daubert specifies procedural formalities derived from the very strong scientific philosophies of positivism and elevates one particular view of causation – Popperian falisification • Daubert standards • Evidence must be “scientific” – grounded in methods and procedures of science • Evidence/research must be validated by appropriate techniques (significance testing, examination of error rates) • Materiality • Peer review • Joiner softened Daubert to give more flexibility to judges
Causation in Law • Purposes of Science – develop and test theories that enhance: • prediction • control • understanding • Good theories are good causal stories • Good theories are replicable under a variety of sampling and measurement conditions
Elements of Causal Theories • The distinction between causal theory and causal explanation • On need not demand that the precise causal mechanisms can be tested in order to make a causal claim, but instead observe that there is a consistent relationship between an outcome and an event • “A hit B in the head and he died” versus “A’s assault gave B led to his death” • Critical elements • Correlation (or “continguity between presumed cause and effect”) • Temporal precedence • Absence of spurious (“third party” effects) • Constant conjunction (“cause-present/cause-absent” requirement) – Hume • Falsification – threshold for falsification? How negative observations do we need to disprove a theory?
Experimental versus Epidemiological Causation • Experiments test specific hypotheses through manipulation and control of experimental conditions • Epidemiological studies presumes a probabilistic view of causation based on observations of phenomena with a natural distribution across populations • Attempt to isolate and control for mediating factors and multiple causes to isolate specific causal effects of interest (example … innoculations, mercury exposure and autism)
Criteria for Causal Inference • Strength (is the risk so large that we can easily rule out other factors) • Consistency (have the results have been replicated by different researchers and under different conditions) • Specificity (is the exposure associated with a very specific disease as opposed to a wide range of diseases) • Temporality (did the exposure precede the disease) • Biological gradient (are increasing exposures associated with increasing risks of disease) • Plausibility (is there a credible scientific mechanism that can explain the association) • Coherence (is the association consistent with the natural history of the disease) • Experimental evidence (does a physical intervention show results consistent with the association) • Analogy (is there a similar result to which we can draw a relationship) Source: Sir Austin Bradford Hill, The Environment and Disease: Association or Causation, 58 Proc. R. Soc. Med. 295(1965)
Errors in Causal Inference • Two Types of Error • Type I Error (α) – a false positive, or the probability of falsely rejecting the null hypothesis of no relationship • Type II Error (β) – a false negative, or the probability of falsely accepting the null hypothesis of no relationship • The two types of error are related in study design, and one makes a tradeoff in the error bias in a study • Statistical Power = 1 – β -- probability of correctly rejecting the null hypothesis
Scientific Process • From theory, specify a conceptual model of causal relationships, translate relationships into constructs, operationalize constructs into measures, and test • Example – deterring tax cheaters • Choices between experimental designs and epidemiological designs • Both are valid paths to causal inference
Types of Research Designs • Case studies • good for generating hypotheses, for understanding and illustrating causal linkages • Not good for testing hypotheses, or for generalizing to other populations • Correlational studies • studies that assess simultaneous changes in independent and dependent variables. • Example: income levels and voter preferences on surveys • Example: diet and disease (epi causation model) • You can still make predictions from correlational studies if you have ruled out other causes, but you cannot achieve “control” without understanding directionality of effect. • True experiments • random assignment of subjects to groups, unequal treatment of similarly situated people • Examples: Perry PreSchool, MTO • Quasi-experiments • Nonrandom assignment, with approximations and control for between-group differences • Selection effects, use propensity scores to adjust for selection differences
Elements of Design • Measurement of variables • Levels of measurement (higher is better) • Reliability of measures • Scale construction and data reduction • Samples • Random, Cluster, Multi-stage cluster, etc. • Specificity of sample to question and population (materiality) • Power considerations • Methods of analysis • Should provide clear test of hypothesis
Data • Types of measures • Normal distributions are preferable but not always attainable, adjust statistics to reflect real distributions • Transformations sometimes ok • Analyses • Compare means • Identify predictors of trends, separately or in combination with other predictors (regressions) • Controls for spurious and competing effects • Panel data – deal with time (serial correlation or autoregression) • Spatial data – deal with spatial dependence • Use graphs to show error rates
Figure 1. Homicides by Executions (lagged), Controlling for State Population, 1977-98 Source: Richard A. Berk, New Claims about Executions and General, Journal of Empirical Legal Studies, 2005
Internal Validity Threats • History – local factors • Maturation of subjects – they change • Test Effects – subjects figure out test • Instrumentation – biased instruments • Regression to the Mean – “what goes up…” • Selection Bias I – non-equivalent groups • Mortality – subjects leave experiment • Testing Effects – you know you’re being studied • Reactivity – reactions to the researcher rather than the stimulus
External Validity Threats • Selection Bias II -- groups are unrepresentative of general populations • Multiple treatment inference -- more than one independent variable operating • Halo effects -- conferring status or label that influences behavior • Local history – changing contexts • Diffusion of treatment -- controls imitate experimental subjects • Compensatory equalization of treatment -- controls want to receive experimental treatment • Decay -- erosion of treatment • Contamination -- C's receive some of E treatment
Types of Samples • Probability Samples • Simple Random Samples • Stratified Random Samples • Cluster Samples • Matched Samples (Case Controls) • Non-Probability Samples • Systematic Samples • Quota Samples • Purposive Samples • Theoretical Samples
Multivariate Models • Ordinary Least Squares (OLS) Regression, or Multiple Regression • tells you which combination of variables, and in what priority, influence the distribution of a dependent variable. • It should be used with ratio or interval variables, although there is a controversy regarding its validity when used with ordinal-level variables. • OLS regression is used more often in survey research and non-experimental research, although it can be used to isolate a specific variable whose influence you want to test • You can introduce interaction terms that isolate the effects to specific subgroups (eg, race by gender). • If you do it right, you can control and eliminate statistical correlations between the independent variables • Logistic Regression is a form of regression specifically designed for binary dependent variables (e.g., group membership)
How Good is the Model? What Does It Tell Us? • Most multivariate models generate probability estimates for each variable in the model, and also for the overall model • Model Statistics: “model fit” or “explained variance” are the two most important • Independent Variables • Coefficient estimate • Standard Error • Statistical Significance • Omitted variable biases • TV Violence example: who chooses to watch TV? Are those factors also related to violence? • E.g., thrill-seeking
Alternatives to Statistical Significance • Odds Ratio – the odds of having been exposed given the presence of a disease (ratio) compared to the odds of not having been exposed given the presence of the disease (ratio) • Risk Ratio – the risk of a disease in the population given exposure (ratio) compared to the risk of a disease given no exposure (ratio, or the base rate) • Attributable Risk – (Rate of disease among the unexposed – Rate of disease among the exposed) ______________________________________________________ (Rate of disease among the exposed)