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Current Health Concerns: Tuberculosis

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Current Health Concerns: Tuberculosis

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    1. Current Health Concerns: Tuberculosis Saharwash Jamali Hamna Jaffar

    3. Some facts… Affects 2billion people 1.6million deaths in 2005 (WHO) Is prevalent with sufferers of HIV; causes most of their deaths. Is, seemingly, on the decline.

    5. Pakistan Facts and Figures. TB quite high High burden country Far out places hard to reach with aid Increased awareness, figures still increasing though (WHO) use information from WHO fact sheets. Have hard copies present.use information from WHO fact sheets. Have hard copies present.

    6. About TB Caused by mycobacterium tuberculosis Mainly pulmonary TB Can spread to other locations in body Can remain dormant in body; asymptomatic carriers ? may develop active TB later in life. explain the mechanisms mainly from microbiology book.explain the mechanisms mainly from microbiology book.

    7. Identification of TB Acid fast bacilli, Ziehl-Neelson staining – culture Molecular techniques – nucleic acid amplification test, polymerise chain reaction (PCR)

    9. Treatment 1st line drugs (chemotherapeutic) Begin with 2 drugs to stop TB resistance developing with just one. Long term 12-18months, short course 6 months Directly observed therapy Complications ? resistance MDR-TB, XDR-TB

    10. Vaccinations Produced from Bacille-Calmette-Guerin (BCG) attenuated strain of M.Bovis 80% protectiveness conferred, provides macrophages with killing ability

    11. WHO Aims and Targets 2006 Stop TB Strategy ?plan to eradicate TB by 2050 DOTS enhancement and expansion Address the growing concern of MDR-TB and XDR-TB Awareness

    12. Resources Lippincotts, Microbiology 2nd Edition http://www.who.int/tb/en/ (WHO website) www.wikipedia.org (Wikipedia, medical students bible) Google Images

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