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RenalNeuroCardiovascular. Physiology. ChemicalCellularTissueOrganSystemOrganism. Levels of Organization. Maintaining boundaries-internal/externalResponsiveness-stimuli/responseMovement-somatic/visceralGrowth-increase in biomass/differentiationDigestion-breakdown of ingested foodMetabol
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1. Microscopic Anatomy- Cytology, Histology
Gross (Macroscopic)Anatomy-Surface, Regional, Systemic
Embryology,Comparative Anatomy-Emphasizes morphology
Anatomical specialties-Medical/Surgical, and Radiographic Anatomy
2. Renal
Neuro
Cardiovascular
3. Chemical
Cellular
Tissue
Organ
System
Organism
4. Maintaining boundaries-internal/external
Responsiveness-stimuli/response
Movement-somatic/visceral
Growth-increase in biomass/differentiation
Digestion-breakdown of ingested food
Metabolism-sum of biochemical processes
Excretion-waste products
Reproduction-cellular/organismal levels
5. The Language of Anatomy Anatomical position
Axial
Appendicular part
6. Body Planes and Sections Sagittal:mid, para
Frontal/Coronal
Transverse/Horizontal
7. Posterior/Dorsal
Anterior/Ventral
Superior/Cranial
Inferior/Caudal
Lateral
Medial
Proximal
Distal
Superficial
Deep
8. Body Cavities Dorsal-cranial,vertebral
Ventral-thoracic (pleural, pericardial), abdominopelvic
9. Membranes in Ventral Body Cavity Visceral serosa
Parietal serosa
Serous fluid
Organ association
Pericardium
Pleura
Peritoneum
10. Umbilical region
Epigastric region
Hypogastric region
Inguinal regions (right/left)
Lumbar regions (right/left)
Hypochondriac regions (right/left)
11. Right Upper
Left Upper
Right Lower
Left Lower
12. Basic unit of all multicellular organisms
Smallest structural unit producing all vital functions
Pre-existing cells produce cells
13. Cell Membrane
Cytosol
Organelles
Inclusions
14. Physical isolation: Extra/intracellular barrier
Regulation of exchange
Sensitivity:Affected by changes in extracellular fluid; receptors for recognition and communication; alterations affect physiology
Structural support
15. Diffusion
Osmosis
Filtration-Hydrostatic pressure forces water across membrane; solutes selected according to size.
Facilitated diffusion
16. Active transport-Na, K, Ca, Mg
Endocytosis-phagocytosis, pinocytosis
17. The cellular material between the plasma membrane and nucleus;site of most cellular activities.
EM has revealed that it consists of cytosol, organelles, and inclusion bodies.
18. Viscous, semitransparent fluid substance
Complex mixture of salts
Dissolved proteins (enzymes)
Amino acids
Lipids
Low carbohydrate [ ]
19. Non functional units/chemical substances
Glycosomes-hepato and myocytes
Lipids-adipocytes
20. Specialized cellular compartments
Non membranous- cytoskeleton, centrioles and ribosomes
Membranous- mitochondria, peroxisomes, lysosomes, nucleus,endoplasmic reticulum, and Golgi apparatus.
21. Intracellular network that supports cell’s structures & providing machinery to generate various cell movements
Components:microtubules, microfilaments
22. Thinnest elements of the cytoskeleton
Primary protein: actin
Forms dense cross-linked network under cell membrane
Involved in motility or changes in cell’s morphology.
23. Elements with largest diameter; spherical protein subunits (tubulin);determine cell’s overall morphology and organelle distribution.
Functions as primary component of cytoskeleton/anchor organelles; can adhere to organelles for intracellular movement
24. Microscopic, finger-shaped projections of membrane; increase surface area (absorption) (jejunum/ileum, kidneys).
Small, barrel shaped oriented at right angles to each other (nine triplets); evident during cell division; form bases; lacking in osteocytes/mature RBCs
25. Contain nine groups of microtubule doublets surrounding central pair (9+2)
Basal body anchor
Exposed aspect of cilia covered by membrane and “beat” rhythmically
Propel substances across cell surface
Substantially longer projections
Propels cell
26. Small, dark staining granules composed of ribosomal RNA
Two globular subunits (small, large)
Free ribosomes produce soluble proteins that will function in the cytosol
Membrane-bound (fixed) ribosomes synthesize proteins destined for cellular membranes or cellular export.
27. Threadlike, double membraned organelle
Inner membrane forms cristae (ATP)
Number may vary according to cell type
DNA/RNA
Cellular respiration
28. Gene containing control center
Controls synthesis of proteins
Numbers vary: (osteoclasts, hepatocytes, myocytes, RBCs)
Shapes vary: spherical,elongate
Has three distinct regions: nuclear envelope, nucleoli, and chromatin.
29. Dark staining spherical bodies located within nucleus responsible for ribosomal production
Non-membrane bound
Typically one or two per cell
Subunits assembled
30. Composed of equal amounts of DNA and globular histone proteins
Chromosome-condensed chromatin coils forming short “barlike” bodies.
31. Network of intracellular membranes and cisternae
Functions: (1) Synthesizes carbohydrates, lipids, and proteins; (2) Transportation
32. Manufactures secreted proteins
Continuum of RER
Lipid metabolism and synthesis/cholesterol-steroid synthesis
Absorption/transport lipids-detoxification
33. Principal “traffic director” for cellular proteins
Modifies, concentrates, and packages
“Receiving” side is cis face, “shipping” side is trans face
Secretory vesicles pinch off from trans face and fuse to membrane.
34. Digests particles taken in by endocytosis
Degrade worn-out or nonfunctional organelles/break down nonuseful tissues
Metabolic functions: glycogenolysis; releasing of ThyH from thyroid cells
Breakdown of bone to release Ca ions
35. Membranous sacs containing powerful enzymes(oxidases/catalases)
Oxidases use O2 to detoxify alcohol and formaldehyde
Numerous in hepatocytes and kidney cells
Self replicating/do not arise from Golgi apparatus