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Figure 1

Figure 1. Figure 2. Somatic Mutation Summary. tumor mutant reads > 10 normal mutant read = 0 tumor mutant fraction > 0.1 normal reference reads > 10. 1030478A28. 1050716A. 3051000A. 98-07-F009a. Figure 3. validation by sanger sequencing of gDNA. P952R. normal. ESYT1. tumor.

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Figure 1

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  1. Figure 1

  2. Figure 2 Somatic Mutation Summary tumor mutant reads > 10 normal mutant read = 0 tumor mutant fraction > 0.1 normal reference reads > 10 1030478A28 1050716A 3051000A 98-07-F009a

  3. Figure 3 validation by sanger sequencing of gDNA P952R normal ESYT1 tumor K217Q normal RYBP tumor

  4. Figure 3B Allelic gene expression analysis of mutated allele Look for better example?

  5. Distribution of Ratio of cDNAras over gDNAras ras = mutant/(wt +mutant) Ratio of cDNA-ras / gDNA-ras Mean = 1.54, p-value = 0.0262

  6. Table 1 Samples used in this study

  7. Table 2 Number of mutation validated by sanger sequencing of gDNA

  8. Table 3

  9. RNA-seq of CGI samples? • Identify mutations and gene expression in large number of genes • Using alellic gene expression can we classify mutations into driver and passenger? • mRNA-seq of breast cancer samples selectively identified driver mutations?

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