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Ch. 4 Part 3. Connective tissues. Connective Tissue. Most abundant and widely distributed tissues in the body Functions: Binds together, supports and strengthens other body tissues Protects and insulates internal organs Compartmentalizes structures such as skeletal muscles
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Ch. 4 Part 3 Connective tissues
Connective Tissue • Most abundant and widely distributed tissues in the body • Functions: • Binds together, supports and strengthens other body tissues • Protects and insulates internal organs • Compartmentalizes structures such as skeletal muscles • Serves as major transport system within the body • Primary location of stored energy reserves • Main source of immune responses
Connective Tissue • Consists of 2 basic elements • Extracellular matrix • Material located between its widely spaced cells • Consists of protein fibers and ground substance • Usually determines characteristics (ex: bone – hard and inflexible) • Cells
Connective Tissue Cells • Vocab • Blast = to bud or sprout (immature cells) • Fibroblast, chondroblast, osteoblast • Cyte (mature cells) • Chondrocyte, osteocyte - “blast gives rise to cyte”
Connective Tissue Cells • Macrophages • Irregular shape with short branches • Where: wandering and fixed (lungs, spleen) • Function: engulf bacteria and cellular debris • Fibroblasts • Large, flat cells with branches • Where: several types of tissue • Function: migrate through C. T. secreting fibers
Connective Tissue Cells • Plasma cells • Small • Where: most places, especially gastrointestinal and respiratory tracts • Function: secrete antibodies for immune response • Mast cells • Where: alongside blood vessels • Function: produce histamine for inflammatory response; can bind to and kill bacteria
Connective Tissue Cells • Adipocytes • Also called fat or adipose cells • Where: deep to skin and around organs • Function: store triglycerides (fats) as energy • White blood cells • Not normally in C. T. but can migrate there in response to infection
Checkpoint • In what ways do connective tissues differ from epithelia? • What are the features of the cells of connective tissue?
Extracellular Matrix • Two major components • Ground substance • Component of C. T. between cells and fibers • Fibers • Collagen fibers, elastic fibers, reticular fibers
Connective Tissue Types • Embryonic – we will not study • Mature – we will study • Loose • Areolar, adipose • Dense • Cartilage • Hyaline, fibrocartilage, elastic • Bone • Liquid • Blood
Mature Connective Tissue Types • Areolar C. T. • Contains: fibroblasts, macrophages, plasma cells, mast cells, adipocytes, white blood cells, collagen fibers, elastic fibers, and reticular fibers • Where: form subcutaneous layer – attaches skin to underlying tissues • Adipose • Single cells filled up with single, large triglyceride droplet • Cytoplasm and nucleus pushed aside • Found everywhere areolar is found • Requires blood flow – heavier = more blood vessels = high blood pressure
Mature Connective Tissue Types • Cartilage • Collagen and elastic fibers in a gel-like substance • Can endure stress • Chondrocytes – mature cartilage cells; occur singly or in groups within lacunae • Has no blood supply – heals poorly after injury • 3 types – hyaline, fibrocartilage, and elastic
Mature Connective Tissue Types • Bone • Also called osseous tissue • Includes marrow, endosteum, periosteum • Basic unit of compact bone is osteon or Haversian system • Blood • Consists of: plasma, red blood cells, white blood cells, platelets
Checkpoint • Describe the following: • Areolar connective tissue • Adipose tissue • Cartilage • Bone tissue • Blood tissue