NSF Programs Fostering Innovation in Bioengineering

1. NSF Programs Fostering Innovation in Bioengineering Semahat Demir, Ph.D. Program Director Biomedical Engineering & Research to Aid Persons with Disabilities (BME/RAPD) Division of Bioengineering and Environmental Systems National Science Foundation BME- Innovation, Design and Entrepreneurship Alliance (IDEA) September 28, 2005 Baltimore, MD

2. Outline • Vision and strategic goals of NSF • NSF Merit Review Criteria • NSF Disciplines • NSF Programs that Foster Innovation in Bioengineering • Engineering Directorate • Other Directorates • Interagency Activity and Working Groups • Interagency Funding Programs for Bioengineering • Concluding Remarks

3. NSF Vision NSF: Where Discovery Begins Enabling the Nation’s future through discovery, learning and innovation.

4. NSF’s Strategic Outcome Goals • People – Develop a diverse, internationally competitive and globally-engaged workforce of scientists, engineers and well-prepared citizens • Ideas – Enable discovery across frontier of science and engineering connected to learning, innovation and service to society • Tools – Provide broadly accessible, state-of-the-art information bases and shared research and education tools

5. NSF Merit Review Criteria • Criteria include: • What is the intellectual merit and quality of the proposed activity? • What are the broader impacts of the proposed activity?

6. What is the intellectual merit of the proposed activity? Potential Considerations: • How important is the proposed activity to advancing knowledge and understanding within its own field or across different fields? • How well qualified is the proposer (individual or team) to conduct the project? (If appropriate, the reviewer will comment on the quality of prior work.) • To what extent does the proposed activity suggest and explore creative and original concepts? • How well conceived and organized is the proposed activity? • Is there sufficient access to resources?

7. What are the broader impacts of the proposed activity? Potential Considerations: • How well does the activity advance discovery and understanding while promoting teaching, training and learning? • How well does the activity broaden the participation of underrepresented groups (e.g., gender, ethnicity, disability, geographic, etc.)? • To what extent will it enhance the infrastructure for research and education, such as facilities, instrumentation, networks and partnerships? • Will the results be disseminated broadly to enhance scientific and technological understanding? • What may be the benefits of the proposed activity to society?

8. Additional Criteria Specific to the solicitation • Requirements and expectations • Management plan • Dissemination plan

9. NSF Disciplines & Structure • Biological Sciences (BIO) • Computer and Information Sciences and Engineering (CISE) • Education and Human Resources (EHR) • Engineering (ENG) • Geosciences (GEO) • Mathematical and Physical Sciences (MPS) • Social, Behavioral And Economic Sciences (SBES) • Polar Programs • Cyberinfrastructure

10. Engineering (ENG) Directorate ENG Divisions • Bioengineering & Environmental Systems (BES) • Biomedical Eng & Research to Aid Persons with Disabilities (BME/RAPD) Program • Civil & Mechanical Systems (CMS) • Chemical and Transport Systems (CTS) • Design and Manufacturing Innovation (DMI) • Grant Opportunities For Academic Liaison with Industry (GOALI) • Electrical & Communications Systems (ECS) • Engineering Education & Centers (EEC) • Engineering Research Centers (ERC) • Partnership for Innovation Program • Industry/University Cooperative Research Centers Program Office of Industrial Innovation (OII) • Small Business Innovation Research (SBIR) and Small Business Technology Transfer Program (STTR)

11. BME/RAPD Program Fostering Innovation • CAREER, investigator-initiated, SGER projects • High risk high return projects • Funding of BME Senior Design Projects • Funding of BME- Innovation, Design and Entrepreneurship Alliance (IDEA) • BME-IDEA Meeting (PI: Paul Yock) • BME-IDEA Contest (PI: Phil Weilerstein)

12. NSF Engineering Research Centers (ERCs) with Products in Clinical Use BioEngineering Cluster • MIT - - Bioprocess Engineering, 1985 and 1995 (graduating in 05) • Georgia Tech with Emory University School of Medicine- - Engineering of Living Tissue, 1998 • Johns Hopkins with CMU and MIT, Brigham Women’s Hospital and Johns Hopkins University Hospital - - Computer Integrated Surgical Systems, 1998 • Vanderbilt University with Harvard-MIT, Northwestern Univ. and U. of Texas-Austin - - VaNTH ERC for Bioengineering Educational Technologies,1999 • U. of Southern California with Caltech and UC-Santa Cruz –Biomimetic Microelectronic Systems, 2003 • U. of Michigan with Mich. St., & Mich. Technological Univ. - - Wireless Integrated Microsytems, 2000 • Northeastern U. with Boston U., U. of Puerto Rico-Mayaguez (UPRM), & Rensselaer - - Subsurface Sensing & Imaging Systems, 2000 • Caltech - - Neuromorphic Systems, 1995, (graduating in 05)

13. Other Funding Opportunities for Innovation in Bioengineering at NSF • Science and Technology Centers (STCs) • Office of Integrative Activities • Integrative Graduate Education and Research Training (IGERT) Initiatives • Div Graduate Education (Directorate Education & Human Resources) • Combined Research-Curriculum Development & Educational Innovation Program (CRCD) • Div Experimental & Integrative Activities (Directorate for Computer & Information Science and Engineering) • Priority Areas • Interagency Programs

14. Role of Interagency Efforts in Fostering Bioengineering Innovation • Interagency Activity Groups for Bioengineering • Interagency Working Groups for Bioengineering • Interagency Funding Programs for Bioengineering

15. Interagency Activity Groups and Working Groups for Bioengineering • The DHHS Medical Technology Innovation Task Force • Image Guided Interventions (IGI) Committee • NSF Scholar in Residence at FDA Program • NIH/NCI Network for Translational Research in Optical Imaging (NTROI) • Interagency Modeling and Analysis Group (IMAG) • NIH Biomaterials and Medical Implant Science (BMIS) Committee • Multi-Agency Tissue Engineering and Sciences (MATES) Group • Working Group on the Interface of the Life Sciences and Physical Sciences • Biomass Research and Development Board

16. INTERAGENCY PROGRAMS FOR BIOENGINEERING • Collaborative Research in Computational Neuroscience (NSF/NIH) http://www.nsf.gov/pubs/2004/nsf04514/nsf04514.pdf • NIH-NSF Bioengineering and Bioinformatics Summer Institutes (BBSI) http://bbsi.eeicom.com/ • Quantitative Systems Biotechnology (2005 ended) http://www.nsf.gov/pubs/2004/nsf04516/nsf04516.pdf

17. INTERAGENCY PROGRAMS FOR BIOENGINEERING (Cont’d) • Joint DMS/BIO/NIGMS Initiative to Support Research in the Area of Mathematical Biology http://www.nsf.gov/pubs/2004/nsf04572/nsf04572.htm • DDDAS: Dynamic Data Driven Applications Systemshttp://www.nsf.gov/pubs/2005/nsf05570/nsf05570.pdf • Interagency Opportunities in Multi-Scale Modeling in Biomedical, Biological, and Behavioral Systems (NSF, NIH, NASA, DOE) http://www.nsf.gov/pubs/2004/nsf04607/nsf04607.pdf

18. Concluding Remarks • Innovation in Bioengineering • Novel ideas • “Integrative” approaches; complex/open-ended problems • Innovation leading to products and clinical use • Better health care delivery; economic growth • Integration of research and education for innovation • All innovations come from education • “Real world experiences”; teaching innovation and entrepreneurship • NSF Programs Fostering Innovation in Bioengineering • BME/RAPD, SGER, ERC, SBIR, STTR, GOALI, STC, IGERT, CRCD • Future: Collaborations • Interagency Activity and Working Groups for Bioengineering • Interagency Funding Programs

19. Thanks for the invitation! www.nsf.gov