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Two Common Questions about NIH Randall Stewart, Ph.D. Program Director NINDS, NIH October 7, 2012

Two Common Questions about NIH Randall Stewart, Ph.D. Program Director NINDS, NIH October 7, 2012. Where’s the Money? How do I get Some?. Conflicts of Interest. Stock options in two companies: Intrexon , Inc. and Graybug , LLC. Today’s Topics.

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Two Common Questions about NIH Randall Stewart, Ph.D. Program Director NINDS, NIH October 7, 2012

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  1. Two Common Questionsabout NIHRandall Stewart, Ph.D.Program DirectorNINDS, NIHOctober 7, 2012 Where’s the Money?How do I get Some?

  2. Conflicts of Interest Stock options in two companies: Intrexon, Inc. and Graybug, LLC.

  3. Today’s Topics 1. NIH grants and processes2. How understanding NIH and its processes can help improve probability of NIH support

  4. Recurrent Themes • Need a good idea about how to answer an important question • Need to align YOUR goals with funding agency goals • Reviewers need to be able to understand: • WHAT you want to do? • WHY it is important? • Can YOU do it?

  5. “The” NIH The “I word” is plural! There are 24 different Institutes and Centers ("ICs") that can award grants. Each one has: • Different missions • Different funding priorities • Different types of grants they support • Different procedures for making funding decisions

  6. Avoid Unpleasant Surprises Which IC supports YOUR research area? Which IC uses the type of grant you want? What are the rules?

  7. Who Supports My Research? What do IC web sites say? What grants have been funded? NIH RePORT What is being solicited? NIH Funding Opportunity Announcements (FOA) NIH Guide

  8. IC Websites • Each institute or center will be xxx.nih.gov • Examples: • NINDS.NIH.GOV • NIMH.NIH.GOV • Use your favorite search engine

  9. What has been funded? • NIH RePorter (report.nih.gov) • Fragile X Mental Retardation Protein (FMRP)

  10. What is being solicited? • ALL applications must be responding to a Funding Opportunity Announcement (FOA) • Some FOA very specialized • Some FOA “generic” = Parent FOA • SOME FOA are listed on Institute Web sites • ALL FOA are published in the weekly NIH Guide for Grants and Contracts

  11. Use “The Guide” • Official Name: The NIH Guide for Grants and Contracts • Published weekly • Includes ALL NIH Funding Opportunities AND • ALL Policy Changes

  12. Don’t Miss Opportunities • Subscribe to the weekly Guide LISTSERV • Search: NIH guide listserv

  13. Types of Grants F series K series R series U series

  14. NINDS Training Office Stephen Korn Search: NINDS Stephen Korn

  15. What happens to an application? Grants.gov NIH eRA Receipt & Referral Study Section FUNDING DECISION Institute staff, Council Institute Director

  16. New and Early Stage Investigators NEW Investigator (NI) : Has never competed successfully for an “R01” before. Early Stage Investigator (ESI): An NI who completed doctoral training less than 10 years ago.

  17. NI/ESI R01 Applications • Reviewed together • Goal: Same success rate for NI/ESI R01s as for new R01s from “established” investigators

  18. Increasing p(Success) Propose research that takes advantage of YOUR training, YOUR expertise, and YOUR environment. State hypotheses explicitly; Do not assume readers will “know what you mean” Make it easy to understand significance & rationale; Have an explicit timeline; Be realistic

  19. Increasing p(Success) Help Reviewers do their job Make the application reader-friendly Make sure your application addresses ALL of the review criteria Do not be sloppy; Follow the directions Solicit criticism EARLY

  20. Getting Advice Solicit it from successful RECENT grant applicants Have them READ your proposal as written; do NOT just talk with them about your ideas Solicit the criticism early enough to take advantage of it!

  21. How Do I Get Funds? Important Idea Matched FOA and NIH Institute(TALK to NIH Program Staff!) Application that Study Section views as better than most of the others!

  22. Contact Information stewartr@ninds.nih.gov

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