1 / 69

Connective Tissue

Discover the major classes of connective tissue - fat, fibrous, cartilage, bone, and blood. Learn about the components like ground substance, fibers, and cells that make up the matrix. Understand the roles of interstitial fluid, cell adhesion proteins, and proteoglycans. Delve into the types of protein fibers including collagen, elastic, and reticular fibers. Uncover the functions and characteristics of connective tissue components in maintaining bodily support and protection.

Download Presentation

Connective Tissue

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Connective Tissue A study in diversity

  2. Connective Tissue

  3. 4 major classes • Connective Tissue • Fat • Fibrous

  4. 4 major classes • Connective Tissue • Fat • Fibrous • Cartilage

  5. 4 major classes • Connective Tissue • Fat • Fibrous • Cartilage • Bone

  6. 4 major classes • Connective Tissue • Fat • Fibrous • Cartilage • Bone • Blood

  7. 4 major classes

  8. 4 major classes

  9. 4 major classes

  10. 4 major classes

  11. Function of Connective Tissue • Support

  12. Function of Connective Tissue • Support • Protection

  13. Function of Connective Tissue • Support • Protection • Insulation

  14. Function of Connective Tissue • Support • Protection • Insulation • Transport

  15. Common Characteristics ? • They originate from the embryonic mesoderm

  16. Common Characteristics ? • They originate from the embryonic mesoderm • Vasculature varies from avascular to vascular

  17. Common Characteristics ? • They originate from the embryonic mesoderm • Vasculature varies from avascular to vascular • Makes a nonliving extracellular matrix

  18. All connective tissue is made up of the following elements :

  19. All connective tissue is made up of the following elements : • Ground substance

  20. All connective tissue is made up of the following elements : • Ground substance • Fibers

  21. All connective tissue is made up of the following elements : • Ground substance • Fibers • Cells

  22. The ground substance and fibers make up the matrix

  23. Ground Substance. • This is a featureless substance that is made up of water and proteins , much like raw egg whites in appearance and consistency.

  24. The ground substance is made up of the following three components • Interstitial fluid

  25. The ground substance is made up of the following three components • Interstitial fluid • Cell adhesion proteins

  26. The ground substance is made up of the following three components • Interstitial fluid • Cell adhesion proteins • Proteoglycans

  27. Interstitial Fluid • This is a solution that bathes and surrounds the cells of multicellular animals

  28. Interstitial Fluid • This is a solution that bathes and surrounds the cells of multicellular animals • An average person has about 11 liters of interstitial fluid, providing the cells with nutrients and a means of waste removal.

  29. Cell Adhesion Proteins (CAP) • Cell adhesion proteins (CAP) are involved in cell-cell and cell-extracellular matrix binding.

  30. Cell Adhesion Proteins (CAP) • Cell adhesion proteins (CAP) are involved in cell-cell and cell-extracellular matrix binding. • The major classes of cell adhesion molecules are the integrins, cadherins, selectins and the immunoglobulins.

  31. Cell Adhesion Proteins (CAP) • These are the glue that holds the cell and tissue together. They become continuous with the basement membrane and the various types of adhesion proteins such as desmosomes.

  32. Proteoglycans • Are a complex group of proteins modified with sugar groups that control how viscous the ground substance is.

  33. Proteoglycans • Proteoglycans are a major component of the matrix, the “filler” substance existing between cells in a tissue.

  34. Proteoglycans • Proteoglycans are a major component of the matrix, the “filler” substance existing between cells in a tissue. • Examples of these include chondrotin sulfate and hyaluronic acid.

  35. What are the function of these components of the matrix? • Interstitial fluid • Cell adhesion proteins • Proteoglycans

  36. The Matrix

  37. Fibers • There are three types of protein fibers which make up the matrix.

  38. Fibers • There are three types of protein fibers which make up the matrix. • These protein fibers intermingle with the proteins of the ground substance.

  39. Fibers • These proteins are: • Collagen fibers • Elastic fibers • Reticular fibers

  40. Collagen • This is a heavily crossed linked protein and as a result is tough and has a high tensile strength. Grossly collagen appears white.

  41. Collagen • It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content.

  42. Collagen • It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. • Collagen in tissues such as tendon, ligament and skin.

  43. Elastic Fibers • Elastic tissue as the name implies can stretch like a rubber band

  44. Elastic Fibers • Elastic tissue as the name implies can stretch like a rubber band • It is found in the skin and lungs

  45. Elastic Fibers • Elastic tissue as the name implies can stretch like a rubber band • It is found in the skin and lungs • Elastin tends to deplete as people age, resulting in wrinkled or stretched out skin

  46. Old Age

  47. Reticular Fibers • Reticular fibers crosslink to form a fine meshwork (reticulum)..

  48. Reticular Fibers • Reticular fibers crosslink to form a fine meshwork (reticulum). • This network acts as a supporting mesh in soft tissues such as liver and bone marrow and the tissues and organs of the lymphatic system.

  49. Cell Component • In the tissue framework are “resident cells

More Related