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The Radiology of Malignant Neoplasms. Juan F. Yepes, DDS, MD, MPH Spring 2009. The Radiology of Malignant Neoplasms. Malignant Tending to become progressively worse, and resulting in death. The Radiology of Malignant Neoplasms. Carcinoma Sarcoma. The Radiology of Malignant Neoplasms.
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TheRadiologyofMalignant Neoplasms Juan F. Yepes, DDS, MD, MPH Spring 2009
The Radiology of Malignant Neoplasms Malignant Tending to become progressively worse, and resulting in death
The Radiology of Malignant Neoplasms Carcinoma Sarcoma
The Radiology of Malignant Neoplasms Carcinoma A malignant neoplasm made up of epithelial cells.
The Radiology of Malignant Neoplasms Sarcoma A malignant neoplasm usually arising from connective tissue cells, but some are of epithelial cell origin.
1995 Estimated New Cancer Cases, United States Percent Distribution of Sites by Sex* 1995 Estimated Cancer Deaths, United States Percent Distribution of Sites by Sex Melanoma of Skin 2% Oral 2% Lung 33% Pancreas 5% Stomach 3% Colon & Rectum 9% Prostate 14% Urinary 5% Leukemia & Lymphomas 6% All Other 19% Melanoma of Skin 3% Oral 3% Lung 14% Pancreas 2% Stomach 2% Colon & Rectum 10% Prostate 36% Urinary 8% Leukemia & Lymphomas 7% All Other 15% 3% Melanoma of Skin 2% Oral 32% Breast 13% Lung 2% Pancreas 12% Colon & Rectum 5% Ovary 8% Uterus 4% Urinary 4% Leukemia & Lymphoma 13% All Other *Excluding basal and squamous cell skin cancers and in situ carcinomas except bladder The Radiology of Malignant Neoplasms 1% Melanoma of Skin 1% Oral 18% Breast 24% Lung 5% Pancreas 11% Colon & Rectum 6% Ovary 4% Uterus 3% Urinary 8% Leukemia & Lymphoma 19% All Other
The Radiology of Malignant Neoplasms • Poorly defined • Non-corticated • Space occupying • Non-resorption of teeth • Destruction of anatomical structures
Well Defined Poorly Defined
Non-corticated Corticated
The Radiology of Malignant Neoplasms • Poorly defined • Non-corticated • Space occupying • Non-resorption of teeth, usually • Destruction of anatomical structures
The Radiology of Malignant Neoplasms • Poorly defined • Non-corticated • Space occupying • Non-resorption of teeth, usually, but • Destruction of anatomical structures
The Radiology of Malignant Neoplasms if and onlyif
The Radiology of Malignant Neoplasms • Poorly defined • Non-corticated • Space occupying • Non-directional resorption of teeth • Destruction of anatomical structures
The Radiology of Malignant Neoplasms • Poorly defined • Non-corticated • Space occupying • Non-resorption of teeth, usually • Destruction of anatomical structures
The Radiology of Malignant Neoplasms • Destruction of periosteum • Internal structure: trabeculae & calcification • “Unilocular” / “multilocular”
Sunray Spicules Sunburst Appearance
The Radiology of Malignant Neoplasms • Destruction of periosteum • Internal structure: trabeculae & calcification • “Unilocular” / “multilocular”
Benign Neoplasm Malignant Neoplasm Cyst or Benign Neoplasm The Radiology of Malignant Neoplasms
The Radiology of Malignant Neoplasms Carcinoma • Ulceration • Not usually a tumor mass*
The Radiology of Malignant Neoplasms Carcinoma • Primary carcinoma • Secondary (metastatic) carcinoma
The Radiology of Malignant Neoplasms Squamous Cell Carcinoma • Primary squamous cell carcinoma • Secondary squamous cell carcinoma
The Radiology of Malignant Neoplasms Teeth “standing in space”
The Radiology of Malignant Neoplasms Carcinoma involving sinuses
The Radiology of Malignant Neoplasms Carcinoma Sarcoma
The Radiology of Malignant Neoplasms Sarcoma A malignant neoplasm usually arising from connective tissue cells, but some are of epithelial cell origin.
The Radiology of Malignant Neoplasms Sarcoma • Myeloma • Osteosarcoma • Chondrosarcoma • Fibrosarcoma • Ewing’s Sarcoma • Leukemia
The Radiology of Malignant Neoplasms Sarcoma • Myeloma • Osteosarcoma • Chondrosarcoma • Leukemia
The Radiology of Malignant Neoplasms Sarcoma • Mass (tumor) often found • Bone production possible • Mass (tumor) often found
The Radiology of Malignant Neoplasms Sarcoma • Myeloma • Osteosarcoma • Chondrosarcoma • Leukemia
The Radiology of Malignant Neoplasms Sarcoma • Myeloma Multiple Myeloma Solitary Plasmacytoma