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Citow Review Pathology

Citow Review Pathology. 8/2/13. High levels of alpha-fetoprotein are associated with. Endodermal sinus tumors Choriocarcinomas Germinomas Pineoblastomas Teratomas. High levels of alpha-fetoprotein are associated with. Endodermal sinus tumors Choriocarcinomas Germinomas

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Citow Review Pathology

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  1. Citow ReviewPathology 8/2/13

  2. High levels of alpha-fetoprotein are associated with • Endodermal sinus tumors • Choriocarcinomas • Germinomas • Pineoblastomas • Teratomas

  3. High levels of alpha-fetoprotein are associated with • Endodermal sinus tumors • Choriocarcinomas • Germinomas • Pineoblastomas • Teratomas

  4. High levels of human chorionic gonadotropin are seen in • Choriocarcinoma • Embyronal carcinoma • Endodermal sinus tumor • Germinoma • Teratoma

  5. High levels of human chorionic gonadotropin are seen in • Choriocarcinoma • Embyronal carcinoma • Endodermal sinus tumor • Germinoma • Teratoma

  6. Viral inclusions seen in herpes encephalitis are • Basophilic • Called Cowdry B bodies • Found in neurons only • Intranuclear • Only evident several weeks after infection

  7. Viral inclusions seen in herpes encephalitis are • Basophilic • Called Cowdry B bodies • Found in neurons only • Intranuclear • Only evident several weeks after infection

  8. Inclusion Bodies (Alzheimer’s) (CMV, Herpes, SSPE) (Polio) (Pick’s disease) (Parkinsons, Lewy body dis) (rabies) (myoclonic epilepsy) (ALS)

  9. Cowdry A Inclusions

  10. Each of the following is characteristic of Wilson’s disease except • Alzheimer’s type II astrocytes • Atrophy & brownish discoloration of globuspallidus & putamen • Autosomal dominant • Decreased serum ceruloplasmin • Decreased serum copper

  11. Each of the following is characteristic of Wilson’s disease except • Alzheimer’s type II astrocytes • Atrophy & brownish discoloration of globuspallidus & putamen • Autosomal dominant • Decreased serum ceruloplasmin • Decreased serum copper

  12. Wilson’s Disease • Mutation in ATP7B gene (ch. 13) • ATPase transporter that incorporates copper into ceruloplasmin • Low ceruloplasmin, low copper • Alzheimer type II astrocytes • Abnormal LFTs • MRI: hyperintense BG on T2 • Keiser Fleischer rings • Renal tubular acidosis • Cardiomyopathy

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