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Citow Review Pathology. 8/2/13. High levels of alpha-fetoprotein are associated with. Endodermal sinus tumors Choriocarcinomas Germinomas Pineoblastomas Teratomas. High levels of alpha-fetoprotein are associated with. Endodermal sinus tumors Choriocarcinomas Germinomas
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Citow ReviewPathology 8/2/13
High levels of alpha-fetoprotein are associated with • Endodermal sinus tumors • Choriocarcinomas • Germinomas • Pineoblastomas • Teratomas
High levels of alpha-fetoprotein are associated with • Endodermal sinus tumors • Choriocarcinomas • Germinomas • Pineoblastomas • Teratomas
High levels of human chorionic gonadotropin are seen in • Choriocarcinoma • Embyronal carcinoma • Endodermal sinus tumor • Germinoma • Teratoma
High levels of human chorionic gonadotropin are seen in • Choriocarcinoma • Embyronal carcinoma • Endodermal sinus tumor • Germinoma • Teratoma
Viral inclusions seen in herpes encephalitis are • Basophilic • Called Cowdry B bodies • Found in neurons only • Intranuclear • Only evident several weeks after infection
Viral inclusions seen in herpes encephalitis are • Basophilic • Called Cowdry B bodies • Found in neurons only • Intranuclear • Only evident several weeks after infection
Inclusion Bodies (Alzheimer’s) (CMV, Herpes, SSPE) (Polio) (Pick’s disease) (Parkinsons, Lewy body dis) (rabies) (myoclonic epilepsy) (ALS)
Each of the following is characteristic of Wilson’s disease except • Alzheimer’s type II astrocytes • Atrophy & brownish discoloration of globuspallidus & putamen • Autosomal dominant • Decreased serum ceruloplasmin • Decreased serum copper
Each of the following is characteristic of Wilson’s disease except • Alzheimer’s type II astrocytes • Atrophy & brownish discoloration of globuspallidus & putamen • Autosomal dominant • Decreased serum ceruloplasmin • Decreased serum copper
Wilson’s Disease • Mutation in ATP7B gene (ch. 13) • ATPase transporter that incorporates copper into ceruloplasmin • Low ceruloplasmin, low copper • Alzheimer type II astrocytes • Abnormal LFTs • MRI: hyperintense BG on T2 • Keiser Fleischer rings • Renal tubular acidosis • Cardiomyopathy