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Pathology Board Review: Electron Microscopy of Neoplasms and Tumor Entities

Explore EM findings in various neoplasms like oncocytoma, plasmacytoma, renal cell carcinoma, seminoma, squamous cell carcinoma. Detailed images and descriptions for pathology board review.

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Pathology Board Review: Electron Microscopy of Neoplasms and Tumor Entities

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  1. Osler Institute – Pathology Board Review: Electron Microscopy EM of Tumors and Tumor-like Entities

  2. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Oncocytoma • Salivary gland • Parotid • Kidney

  3. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Oncocytoma • Pleomorphic mitochondria • Lamelliform (plate like) mitochondrial cristae • Dense bodies in mitochondria

  4. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Plasmacytoma • Nuclei • Marginated heterochromatin • Prominent profiles of rough endoplasmic reticulum • Immunoglobulin inclusions in RER and nucleus

  5. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Renal Cell Carcinoma • (conventional type) • Long microvilli • Glycogen • Lipid droplets

  6. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Renal Cell Carcinoma • Chromophobe Type • Microvesicles • Hale’s colloidal iron positive • Papillary (chromophil) Type • Abundant mitochondria

  7. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Seminoma • Wandering, ropy, nucleolus • Finely dispersed heterochromatin • Inconspicuous organelles • Intercellular junctions

  8. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Squamous cell carcinoma • Desmosomes • Tonofilament bundles

  9. Electron Microscopy - Osler Institute Pathology Board Review Small Round Cell Tumors

  10. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Small Round Cell Tumors • Ewings Sarcoma • Dispersed heterochromatin • Small nucleolus

  11. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Small Round Cell Tumors • Ewings Sarcoma • Large pools of glycogen

  12. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Small Round Cell Tumors • Rhabdomyosarcoma • Actin-myosin filaments with Z-band • Primitive sarcomeres

  13. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Small Round Cell Tumors • Rhabdomyosarcoma • Ribosome-filament complexes • Small primitive junctions • External lamina

  14. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Small Round Cell Tumors • Neuroblastoma • Cell processes • Secretory granules • Microtubules • Neurofilaments

  15. Electron Microscopy - Osler Institute Pathology Board Review • Neoplasms • Small Round Cell Tumors • Lymphoma (Follicular Center Cell) • No cell junctions

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