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Explore the concepts of homeostasis, pathogens, cancer, and the immune system. Learn about the body's defense mechanisms, types of pathogens, immunity, and diseases like AIDS. Discover how disruptions in homeostasis can lead to illness and the importance of vaccines.
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Warm Up: • What is homeostasis?
Recall: Homeostasis is the regulation of an organism’s internal environment to maintain conditions needed for life When homeostasis is disrupted disease can occur
What is a pathogen? • Cause of infectious disease
Types of pathogens • Virus • Bacteria • Fungus • Parasites • Protists These are microbes: microscopic organisms
What is Cancer? • Characterized by abnormal and uncontrolled cell growth
Why is cancer an example of the body not maintaining homeostasis? • Normally the body controls beginning and end of the cell cycle • If control is lost, abnormal or uncontrolled cell growth can lead to tumors
The Immune System • Mechanisms in an organism that protects body against disease
Antigen Substance foreign to the body that causes an immune response
Body’s 1st Line of Defenses Barriers -Skin barrier -Chemical barriers (saliva, tears, nasal secretions) -Hydrochloric acid in stomach
Body’s 2nd Line of Defenses Non-Specific Response -White blood cell use engulf pathogen
Body’s 3rd Line of Defenses Specific Response involves lymphatic system which filters lymph and blood destroying foreign microorganisms Includes B cell and T cell response
Antibodies • Proteins produced by B lymphocytes (B cells) that specifically react with a foreign antigen
T cells Add this to your notes • Helper T cells activate antibody production in B cells and activates cytotoxic T cells • Cytotoxic T cells destroy pathogens and release chemicals
White blood cells • Some WBCs mark pathogens for destruction while others engulf microbes during an immune response • And yet others produce antibodies
Why do people rarely get the same disease twice? • Memory cells reduce the likelihood of developing the same disease twice
Vaccine • Dead or weakened form of a virus used to stimulate an immune response
Immunity • 2 Types • Inborn Immunity: immunity to disease at birth • Acquired Immunity: develops during lifetime
Acquired Immunity Add this to your notes
Add this to your notes Allergies • Reactions to usually harmless environmental antigens • Mast cells release histamines • Causes a localized inflammatory response • Swollen, itchy eyes, stuffy nose, sneezing • Pollen, dust, dust mites, food
AIDS • Human Immunodeficiency Virus • Attacks white blood cells (CD4) • Weakens patient’s immune system