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Daily Entry. 1. A specialized cell that functions in sending chemical and electrical signals is? 2. A living plant specialized cell that transports sugar? 3. Blood cells with nuclei are referred to as? 4. A specialized cell that has a lot of mitochondria and a flagellum for movement?
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Daily Entry • 1. A specialized cell that functions in sending chemical and electrical signals is? • 2. A living plant specialized cell that transports sugar? • 3. Blood cells with nuclei are referred to as? • 4. A specialized cell that has a lot of mitochondria and a flagellum for movement? • 5. An unspecialized cell?
Video (Both links are to the same video, try the other if one doesn’t work) • http://www.eurostemcell.org/films/a-stem-cell-story/English • http://www.youtube.com/watch?v=2-3J6JGN-_Y
What is a stem cell? Stem cell Stem cell DIFFERENTIATION (specializing) SELF-RENEWAL (copying) Identical stem cells Specialized cells Stem cell= an undifferentiated cell that has not been given a specific job or function yet, once it is given a specific job it is then differentiated/specialized
Why self-renew AND differentiate? 1 stem cell 4 specialized cells 1 stem cell Differentiation - replaces dead or damaged cells throughout your life Self renewal - maintains the stem cell pool
Where are stem cells found? 2. tissue stem cells fetus, baby and throughout life 1. embryonic stem cells blastocyst - a very early embryo
Types of stem cell: 1) Embryonic stem cells
Embryonic stem (ES) cells: Where we find them blastocyst cells inside = ‘inner cell mass’ fluid with nutrients culture in the lab to grow more cells embryonic stem cells taken from the inner cell mass outer layer of cells = ‘trophectoderm’
Embryonic stem (ES) cells: What they can do differentiation embryonic stem cells PLURIPOTENT- capable of developing into any type of cell, these are very important to research all possible types of specialized cells
Embryonic stem (ES) cells: Challenges skin grow under conditions A grow under conditions B neurons embryonic stem cells grow under conditions C blood grow under conditions D ? liver
Types of stem cell: 2) Tissue stem cells
Tissue stem cells: Where we find them surface of the eye brain skin breast intestines (gut) testicles bone marrow muscles
Tissue stem cells: What they can do blood stem cell differentiation found in bone marrow only specialized types of blood cell: red blood cells, white blood cells, platelets MULTIPOTENT-can give rise to other types of cells but it is limited in its ability to differentiate Ex:Bone marrow also contains multipotent stem cells that give rise to all blood cell types but not any other type of specialized cells
Pros vs. Cons • Transplant organs • Discovery of new medicine/drugs • Cure for diseases • Cancer • Skin grafts • Genetic disorders • Injuries and healing • Spinal • Cloning • Ethical/emotional issues • abortion • Religious beliefs • Fear of cloning • Against human experimentation • Long term side affects are unknown and still in progress • Multipotent • Expensive
Think Globally How could stem cell research benefit other countries?
Think-Pair-Share • Think: President Obama recently overturned a ban on federal funds for stem cell research. Should stem cell research be federally funded? • Are you for or against stem cell research? • Pair: Turn to your neighbor and share your thoughts
Left-side Activity • Create a public announcement, newspaper article, flyer, advertisement, t-shirt design ect. Representing your opinion on stem cell research • Include • What a stem cell is • The two types of stem cells • Where stem cells come from • How they can be used • Illustration