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Biology – The Continuity of Life. Objective 2 Explain how DNA is duplicated during DNA replication. DNA Replication. Why? DNA must be copied before mitosis When? Interphase S Where? Nucleus. DNA Replication. Who? DNA Polymerase Adds new complimentary base pairs to a new DNA strand
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Biology – The Continuity of Life • Objective 2 • Explain how DNA is duplicated during DNA replication
DNA Replication • Why? • DNA must be copied before mitosis • When? • Interphase S • Where? • Nucleus
DNA Replication • Who? • DNA Polymerase • Adds new complimentary base pairs to a new DNA strand • Helicase • Unwinds and unzips the DNA strand
DNA Replication • How? (click title for video) 1. Helicase unwinds and unzips DNA 2. DNA Polymerase adds the new bases…remember A-T and C-G 3. The new bases are linked together 4. An enzyme proofreads the new strand 5. The old and new strands wind back up into two double helixes
DNA Replication • Result? • 2 EXACT copies of DNA, each made with an old and a new strand • Mistakes? • Are called MUTATIONS… • …can help you, hurt you, most of the time they DO NOTHING • Error Rate – • 1 letter in 1 billion wrong • 3 mistakes per DNA replication