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Phasors , Capacitors, Impedance. Spin My World Right Round. LPF Application: Gastric Electrical Activity. 60-70 million people suffer from GI disorder Electrically active organ. http://www.virtualmedicalcentre.com/anatomy/gastrointestinal-system/7.
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Phasors, Capacitors, Impedance Spin My World Right Round
LPF Application: Gastric Electrical Activity • 60-70 million people suffer from GI disorder • Electrically active organ http://www.virtualmedicalcentre.com/anatomy/gastrointestinal-system/7 Image from P. Du et al. Biophys J. (2010) 99:2784-2792.
Electrogastrogram and Slow Wave mapping Flexible Electrode Array (256 electrodes) Recording the EGG (6 electrodes) Typical gastric slow wave recording (freq ~ 0.05 Hz) Mapping SW activity with high density electrodes
Real life example Signal of interest Noise (oscillations so fast you can’t see the individual waves) What the electrode records (ruh-roh!)
One possible solution: Low Pass Filter Vout(t) • High frequency components: Kill off (strongly attenuate) • Low frequency components: Pass through essentially untouched
LPF in Action Strongly attenuated 60Hz Barely attenuated 0.05Hz
Raw vs. Filtered Signal INPUT OUTPUT (raw gastric + raw powerline) (filtered gastric + raw powerline)
Capacitors come in all shapes and sizes Typical ones in the lab Some big, some small
These are capacitors too! Cell membrane Icky cells (bacteria)
And so is this! PC board Red = top layer Green = bottom layer
Phasors: Magnitude and Phase Projection onto real axis traces out Acos(wt + f)
Magnitude and Phase http://resonanceswavesandfields.blogspot.com/2007/08/phasors.html#phasor-beating
Phasors! -sinwt coswt -coswt sinwt Rotates in time But we just read off the magnitude and phaseinformation at one instant (usually, t = 0)
Raw vs. Filtered Signal (50 kW) (10 mF) We now interrupt this broadcast to do some phasor math…
Implementing a low pass filter (LPF) Strongly attenuated 60Hz Barely attenuated 0.05Hz
Bode Plot power line gastric cutoff
Get rid of bieber • Beauty and the Beat • Sweet bass line (f <= 150 Hz) • Screechy Bieber vocals (f >= 450 Hz) • Raw song SNR = Bass/Bieber = ½ • Design a circuit that: • increases SNR >= 1 • keeps phase shift for bass frequencies |f|<= 40 deg.