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All pore-forming ion channels are similar in structure

All pore-forming ion channels are similar in structure. Struktur des K-Kanals. Rod MacKinnon Chemie Nobelpreis 2003. Crystal is defined and stabilized by Antibodies.

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All pore-forming ion channels are similar in structure

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  1. All pore-forming ion channels are similar in structure BPZ§4.3

  2. Struktur des K-Kanals Rod MacKinnon Chemie Nobelpreis 2003 BPZ§4.3

  3. Crystal is defined and stabilized by Antibodies BPZ§4.3

  4. Chemistry of Ion Coordination and Hydration Revealed by a K+ Channel-Fab Complex at 2.0 Angstrom Resolution; MacKinnon, R., et al.; Nature, Vol. 414; January 1, 2001 Potassium Channel Receptor Site for the Inactivation Gate and Quaternary Amine Inhibitors; MacKinnon, R., et al.; Nature, Vol. 411; March 8, 2001 Energetic Optimization of Ion Conduction Rate by the K+ Selectivity Filter; MacKinnon, R., et al.; Nature, Vol. 414; November 1, 2001 BPZ§4.3

  5. Ionenselektivität des Natriumkanals BPZ§4.3

  6. BPZ§4.3

  7. Alternative Stacking of K+ (Green) and Water (red) High K+ Concentration (2M) BPZ§4.3

  8. Gating by conformational changes of the tetramer BPZ§4.3

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