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Oxygen Toxicity and ROP

Pulmonary Oxygen Toxicity. Oxygen is probably the most important single factorMost other factors act by increasing need for supplemental oxygen or by alterating the sensitivity to oxygenEffects are mediated by reactive oxygen speciesdirect effectsinflammatory cascadesstimulation of growth facto

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Oxygen Toxicity and ROP

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    1. Oxygen Toxicity and ROP J Baier MD

    2. Pulmonary Oxygen Toxicity Oxygen is probably the most important single factor Most other factors act by increasing need for supplemental oxygen or by alterating the sensitivity to oxygen Effects are mediated by reactive oxygen species direct effects inflammatory cascades stimulation of growth factors

    3. Reactive Oxygen Species Superoxide O2- Hydrogen Peroxide H2O2 Singlet Oxygen O. Lipid Peroxide RCOO. Hydroxyl radical HO.

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