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Actual amount of substance supplied (removed). A = Q x ( Ca – Cv). What determines flow (Q). Q = (Pa – Pv)/R. Low vascular resistance. Q. High vascular resistance (vasoconstriction. Measurement of Q. Electromagnetic flowmeter. Doppler effect. Fick principle. Blood flow velocity.
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Actual amount of substance supplied (removed) A = Q x ( Ca – Cv)
What determines flow (Q) Q = (Pa – Pv)/R
Low vascular resistance Q High vascular resistance (vasoconstriction
Blood flow velocity A= 2cm2 10cm2 1cm2 Q=10ml/s a b c V= 5cm/s 1cm/s 10cm/s V = Q / A
Vascular wall flow
Laminar high flow turbulent laminar velocity
Resistance to blood flow Rt = R1 + R2 + R3…………. Resistance in series 1/Rt = 1/R1 + 1/R2 + 1/R3…. Resistance in parallel R1 PARALLEL SERIES R2 R1 R2 R3 R3
x x x x Redistribution in exercise
What determines R ? Wall tension vasokonstriction vasodilatation
Laplace Pro trubici platí r
Critical closing pressure Q pressure pressure Wall tension
Blood pressure Q = (Pa – Pv)/R
systolic Blood pressure (torr) diastolic Mean velocity cm/sec
Velocity of blood flow A= 2cm2 10cm2 1cm2 Q=10ml/s a b c V= 5cm/s 1cm/s 10cm/s V = Q / A
SYSTOLIC SV elasticity of aorta DIASTOLIC R heart rate
V P