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Infectious Diseases Unit 5 Lesson 5 plan

Infectious Diseases Unit 5 Lesson 5 plan. Do now. Brainstorm in your table groups – What’s in a vaccine?. How do vaccines work?. They stimulate an infectious agent – without being dangerous. B cell. T cell. A vaccine tricks the immune system into responding:.

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Infectious Diseases Unit 5 Lesson 5 plan

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  1. Infectious Diseases • Unit 5 Lesson 5 plan

  2. Do now Brainstorm in your table groups – • What’s in a vaccine?

  3. How do vaccines work? They stimulate an infectious agent – without being dangerous

  4. B cell T cell A vaccine tricks the immune system into responding: The antigen-presenting cell activates the Helper T cell 1. T cell T cell B cell The activated Helper T cell stimulates the B cell to make memory B cells and antibodies 2 But the antigencan’t cause disease – its inert!

  5. Four Ways to Make an Inert Antigen Usually done with heat or chemicals Danger is that they are not all killed 1. Virus that has been completely Inactivated (killed).

  6. Four Ways to Make an Inert Antigen -The virus can be weakened (attenuated) -You take away the genes that cause infection or toxins -Problem is those often code for the antigen as well -Smallpox made like this Virus that has been weakened (attenuated).

  7. Four Ways to Make an Inert Antigen -This is just the antigens themselves -But they often don’t activate the innate immune system -So must stimulate the immune system with and adjuvant -Tetanus made like this 3. Parts of a virus that have been genetically engineered (recombinant protein) 4. Virus that has been genetically engineered so it is not infective (recombinant virus).

  8. Four Ways to Make an Inert Antigen 3. You have control over everything But that’s a lot of engineering Currently scientists are trying to make artificial viruses 1. 4. Virus that has been genetically engineered so it is not infective (recombinant virus). 2.

  9. Which antigen would be best? 1. 3. Parts of a virus that have been genetically engineered (recombinant protein) 4. Virus that has been completely Inactivated (killed). Virus that has been genetically engineered so it is not infective (recombinant virus). 2. Virus that has been weakened (attenuated).

  10. This One! Probably the best way since you have control over everything But again it is the hardest 1. 3. Parts of a virus that have been genetically engineered (recombinant protein) 4. Virus that has been completely Inactivated (killed). Virus that has been genetically engineered so it is not infective (recombinant virus). 2. Virus that has been weakened (attenuated).

  11. What makes a good vaccine? Brainstorm in your table groups –

  12. What makes a good vaccine? • Protection • Sterilizing – Totally prevented or cleared by the immune system • vs • Non-sterilizing immunity – Pathogen is controlled and disarmed, but stays in your system • Number of doses • Is one shot enough? • Immunological memory • Do you need to be revaccinated every year? • Practicality • Does it need refrigeration? • Economical • Is it affordable?

  13. The Great Debate Are vaccines worth the risk? -Take the rest of the period to prepare for the debate by reviewing the materials -Be prepared to take both sides of the issue –It is worth the risk and it is not worth the risk -Remember – everything you say must be based on a source – no opinions!

  14. Homework • Study for your test! • (And have a great vacation)

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