Faculty of Allied Medical Sciences Parasitology (MLPR-201) fall 2013/2014

1. Faculty of Allied Medical SciencesParasitology(MLPR-201)fall 2013/2014

2. Human Parasitology kingdom : Protista (Protozoa) Dr. HamdyBadie M. El-Wakil Prof. of Parasitology & Public Health . Faculty of Allied Medical Sciences. Pharos University In Alexandria,Egypt

3. Intended learning outcomes • By the end of this lecture, students should understand the classification, pathogenicity, clinical importance and clinical features of kingdom : Protista (Pathogenic Protozoa) .

4. Class Lobosea • Class Zoomastigophorea • Class Sporozoa • Class Ciliophora Medical Protozoology Human Parasitology • Class Nematoda • Class Trematoda • Class Cestoda • Class Metacanthocephala Medical Helminthology • Class Insecta • Class Arachnida • Class Crustacea • Class Chilopoda Medical Arthropodology

5. kingdom : Protista (Protozoa) Only a few of the many tens of thousands of protozoa species are pathogenic for humans (I) Pathogenic protozoa: 1- Intestinal: Entamoebahistolytica (Ameba). Giardialamblia (Flagellate). Cryptosporidiumparvum (Sporozoan). 2- Urogenital: Trichomonasvaginalis. 3- Blood and tissues:  Plasmodium species (Sporozoan).  Toxoplasma gondii (Sporozoan).  Trypanosomaspecies (Flagellate).  Leishmania species (Flagellate).

6. The subkingdom protozoa contains the following phyla: • 1- Phylum: Sarcomastigophora: (a) Subphylum: Sarcodina e.g. Amoeba • (b)Subphylum: Mastigophora e.g. Trypansoma •  Digestive and genital tracts •  Blood and tissues. • 2- Phylum: Ciliophora (Ciliates): Balantidium coli Intestinal parasite of man. • 3- Phylum: Apicomplexa: Class: Sporozoa: Asexual and sexual generations (All are parasitic). (e.g. Malaria).

7. Moving: •  Amebas : Move by extending cytoplasmic projections. •  Flagellates : Move by rotating whip – like flagella. •  Ciliates : Move by synchronous beating of hair – like cilia. •  Sporozoa : Generally have non-motile adult forms.

8. Protozoa

9. A.

12. Intestinal Infections There are three principal protozoal intestinal parasites: the ameba Entamobahistolytica, the flagellate, Giardia lamblia and several varieties of sporozoa, Cryptosporidium parvum. Each causes a dysentry which although similar, differs in the site of infection, the severity and secondary consequences.

16. Entamoeba sp. (causing amoebiasis)

18. Pathology (Invasion of the large intestine)

19. Complications

20. Entamoeba histolytica (causing amoebiasis)

21. vulvitis

27. Life Cycle of Balantidium coli

29. Study Questions • Complete the following sentences: • Pathogenic protozoa could be intestinal as……………….,……….. or………………. Like ……….and……………….or Blood and tissues, like……………………….,………………..and…………. • Amebas : Move by………………while Flagellates Move by………………….. • Entamobahistolytica, Giardia lamblia and, Cryptosporidium parvum. Each causes a ………….

30. Assignments • Group of students will be selected for an assignment topic ,one of the parasites that are studied in your course. • The following points should be covered in your assignment sheets: (1) Classification Position: (2) Name of the parasite; (3)Description (Morphological Characters in vivo): (4) Definitive (Final) Host: (5) Intermediate Host: (6) Mode Of Infection: (7) Infective Stage:-. (8) Habitat:- (9) Diagnostic Stage:- (10) Disease:- (11) life cycle

31. Assignments topics Schistosoma spp باسم خالد محمد زغلول طه بسمه مهدي رياض مهدي شابون بسنت اشرف محمد احمد شكري بسنت حسن علي محمد احمد محمود محمد صالح عبد القادر النقيب مراد عادل عبد الفتاح علي حسن مروة محمد عبد السلام محمد محمود مروه محمد علي بريقع

32. Taeniaspp تغريد محمود ابراهيم مصطفى حسام الدين حسين محمد حسين مبروك حسام حسين منصور عبد السميع حماده محمد عشري عبد الحميد نصر مستور مصطفى حميده عبد المولى مصطفي حفني محمود حفني احمد مصطفى كرم الهادي محمد الهادي احمد مصطفى محمد يسري عبد القادر غنيم