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Behzad Nakhaei, M.D. , FICS Fellowship in HepatoBiliary Surgery Mc Gill University. RUQ & Upper Abdomen Inflammation & Infection GallBladder & Biliary System Disorders ( A Problem Solving Lecture ) For Medical Students.
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Behzad Nakhaei, M.D. , FICSFellowship in HepatoBiliary Surgery Mc Gill University RUQ & Upper Abdomen Inflammation & Infection GallBladder & Biliary System Disorders ( A Problem Solving Lecture ) For Medical Students
Common Clinical PresentationsIn RUQ & Upper AbdomenDue to Inflammation & Infection • Pain & Fever • Jaundice & Fever • Mass & Fever • (One / Two Symptoms Dominate in each of these)
Signal the need for: • Complete Blood Count • Liver Function Test • Serum Amylase • PT , PTT • Blood Culture • Chest & Abdominal X ray • Abdominal Ultrasonography
3Most common Scenario:? • Acute Cholecystitis? • OR • Acute Cholangitis? • OR • Acute Pancreatitis?
Pain & Fever? • Upper Abdomen Sepsis == RUQ Pain & Fever • In 2/3 of Cases Biliary Origin • (Acute Cholecystitis, Biliary Colic, Acute Cholangitis) • Acute Pancreatitis • Pneumonia • Hepatitis , Herpes Zoster • Other gastrointestinal Disease • Sono is the most important Screening test for Acute Biliary Infections.
Diagnosis AcuteCholecystitis Biliary Colic Acute Cholangitis Acute Pancreatitis Sono Finding Stone & Thickening of wall Stone in Biliary Tree Stone & Dilatation of CBD Pancreas Enlargement Pain & Fever
Cholecystitis ? • Acute Calculous • Acute Acalculous • Emphysematous • Hydrops • Empyema • Chronic
Risk Factors of Gangrene & Perforationin Acute Cholecystitis • Systemic Toxicity • Emphysematous Cholecystitis • Acalculous Cholecystitis
Fever & Jaundice ? • If the Patient Presents with : • Fever > 38.5 & Jaundice • Leukocytosis & Positive Blood Culture • Stone & Biliary tree dilatation on Sono • Reynolds, Pentad • ( Abdominal Pain, Fever&Chills,Jaundice, Hypotension,Mental confusion ) • Dx is Acute Cholangitis
Cholangitis? • Infection within Biliary tree Due to : • Choledocholithiasis • Choledochal cysts • Bile Duct CA • Sphincteroplasty • Instrumentation of Biliary tree
Cholangitis ? • Acute SuppurativeCholangitis • Cholangiohepatitis • Sclerosing Cholangitis
Acute SuppurativeCholangitis? • Pus within the Biliary tract • Complicated by Obstructive Jaundice • Charcot triad : Jaundice, Chill , Fever • Age Over 70 • ERCP or PTC • Surgical Intervention
Cholangiohepatitis • Most common in China & Hong Kong • Clonorchiasis • Ascariasis • Malaria Hemolysis • E coli & Klebsiella • Toxic Condition • Emergency surgery
Sclerosing Cholangitis • Involve Extra & Intrahepatic Biliary tree • Association with Ulcerative colitis&Crohn • HIV infection has been noted • Most common in middle age men • By Pass operation for Palliation • Liver Transplantation for Cure
Fever & Abdominal Mass? • The origin of Pathology is in the : • GallBladder • Or • Liver
Fever & Abdominal Mass? • Possible Diagnosis Are : • Empyema of GB • Hydrops of GB • Pyogenic Liver Abscess • Liver infected Cysts
Biliary Enteric Fistula &Gallstone Ileus • Between GB & Duodenum 85% • Between GB & Colon 15 % • Can cause Mechanical Obstruction • Most often in Terminal Ilum • Past history of Cholelithiasis is present
Mirizzi,s Syndrome? • A fistula between Hartmann's Pouch & CBD • A Stone in the Ampulla of the GB can erode the CBD and can destroyed CBD Partially or Completely
YOU!!!!!!!! • Try to BE A Sophisticated Person