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Cellular Secretion: Essential for establishment and maintenance of pregnancy.

What cells secrete?. Mucus/AnitmicrobialsProtection for mucosal surfacesMucin-defensins IonsRegulate membrane excitabilityCalciumNeurotransmittersTransmit neural signalsAcetylcholineEnzymesInvolved in digestive processesTrypsinHormonesRegulate cellular functionsInsulinEstrogen/Testo

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Cellular Secretion: Essential for establishment and maintenance of pregnancy.

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    1. Cellular Secretion: Essential for establishment and maintenance of pregnancy. Chapter 9 in Cooper & Hausman

    2. What cells secrete? Mucus/Anitmicrobials Protection for mucosal surfaces Mucin -defensins Ions Regulate membrane excitability Calcium Neurotransmitters Transmit neural signals Acetylcholine Enzymes Involved in digestive processes Trypsin Hormones Regulate cellular functions Insulin Estrogen/Testosterone Antibodies Immune cells IgG, IgA, IgM

    3. How cells secrete Classical secretory pathway ER-Golgi-TGN-Plasma membrane Mediated by signal peptide on protein Membrane-bound vesicles transported on cytoskeletal highways microtubules Constitutive and regulated microfilaments

    4. How cells secrete Non-classical Unconventional secretory pathways Not well-described Proteins translated on free ribosomes in cytoplasm Lysosomes Plasma membrane pores Multivesicular bodies Membrane blebbing.

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