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Bleeding from the Gut Clinical approach. Severity Vital signs Haematocrit Beware ongoing losses Acute onset or chronic blood loss Fe deficiency Stigmata of disease Failure to thrive and grow Purpura Liver and spleen. Site of bleeding. Haematemesis Fresh blood
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Bleeding from the GutClinical approach • Severity Vital signs Haematocrit Beware ongoing losses • Acute onset or chronic blood loss Fe deficiency • Stigmata of disease Failure to thrive and grow Purpura Liver and spleen
Site of bleeding • Haematemesis Fresh blood swallowed, rapid haemorrhage Altered - “coffee ground” gastric acid
Site of bleeding • Bleeding per rectum Fresh blood not mixed with stool low rectum and anus Fresh blood with mucus - dysentery colon and rectum Jellied dark blood intussusception Melaena - tarry black bleeding from higher up
Bleeding from the gut • Bleeding tendency Vitamin K deficiency Hepatic failure Disseminated intravascular coagulation septicaemia, necrotising enterocolitis Thrombocytopaenia haemolytic uraemic syndrome Vasculitis - Henoch Schonlein purpura
Bleeding from the Gut • Swallowed blood Maternal blood swallowed intrapartum Apt test Nose bleed Mouth and pharynx • Oesophagus Varices (portal hypertension) Oesophagitis (peptic or other) Mallory-Weiss tear
Bleeding from the Gut • Stomach Gastritis and erosions Ulcer (peptic, stress) • Small gut Meckel diverticulum Ulcers (peptic and inflammatory) Intussusception Volvulus Polyps
Bleeding from the Gut • Large gut Dysentery (amoebic, bacterial) Intussusception Polyps Ulcerative colitis • Rectum and anus Varices Polyps Trauma Anal fissure
Bleeding from the gutManagement • Resuscitation as required • Stop the bleeding mostly spontaneous vitamin K blood component therapy emergency endoscopic approach
Bleeding from the GutManagement • Identify the site of haemorrhage History Character of blood Upper gut: endoscopy Lower gut: contrast studies isotope scan “Meckel scan” endoscopy • Identify and manage aetiology • Follow-up for recurrence
Dysentery • Mucosal invasion or toxin mediated inflammation with necrosis bacteria - shigella, Esch.coli, others Entamoeba histolytica, trichiuris • Fever, abdominal pain, extraintestinal features • Sometimes onset in “gastro-like” fashion • Major complications