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“Olefin Metathesis” R. H. Grubbs, Tetrahedron, 2004 , 60 , 7117-7140.

Metal Catalyzed Reactions of Hydrocarbons Robert H. Grubbs, Caltech Award #CHE-0410425, equally co-funded with DMR/POL.

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“Olefin Metathesis” R. H. Grubbs, Tetrahedron, 2004 , 60 , 7117-7140.

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  1. Metal Catalyzed Reactions of Hydrocarbons Robert H. Grubbs, Caltech Award #CHE-0410425, equally co-funded with DMR/POL Fundamental mechanistic studies have resulted in a family of ruthenium based catalysts have been developed for the metathesis of olefins. The results of this NSF supported research are now being transitioned into applications in pharmaceuticals, fine chemicals and materials. “Olefin Metathesis” R. H. Grubbs, Tetrahedron,2004, 60, 7117-7140.

  2. Metal Catalyzed Reactions of Hydrocarbons Robert H. Grubbs, Caltech Award #CHE-0410425, equally co-funded with DMR/POL Fundamental mechanistic studies have resulted in a family of ruthenium based catalysts have been developed for the metathesis of olefins. A DOE/Cargill/Caltech/Materia,Inc. research agreement has just been initiated for the use of these catalysts for the conversion of the renewable resource, Seed Oils, into products normally produced from petroleum based materials. A new material will be introduced in the next few months as a commodity product. Replacements for Petroleum based Products Renewable Seed Oils “Olefin Metathesis” R. H. Grubbs, Tetrahedron,2004, 60, 7117-7140.

  3. Metal Catalyzed Reactions of Hydrocarbons Robert H. Grubbs, Caltech Award #CHE-0410425, equally co-funded with DMR/POL Fundamental mechanistic studies have resulted in a family of ruthenium based catalysts have been developed for the metathesis of olefins. These catalysts can be used in the preparation of a variety of polymers, materials and small molecules. The chemistry is now being used to produce a number of pharmaceuticals by ring closing metathesis that are now in phase II trials. Boehringer Ingelheim’s BILN 2061 HCV Serine Protease Inhibitor Hepatitus C Therapeutic GlaxoSmithKline Osteoporosis Therapeutic . “Olefin Metathesis” R. H. Grubbs, Tetrahedron,2004, 60, 7117-7140

  4. Metal Catalyzed Reactions of Hydrocarbons Robert H. Grubbs, Caltech Award #CHE-0410425, equally co-funded with DMR/POL Fundamental mechanistic studies have resulted in a family of ruthenium based catalysts have been developed for the metathesis of olefins. These catalysts can be used in the preparation of a variety of polymers, materials and small molecules. On example of the application in materials is a composite wood-ROMP polymer bat that is now commercialized by Easton Sports. This application demonstrates the environmental tolerance and robustness of the chemistry. Picture or graphic Materia, Inc and Easton Sports

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