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Literature Presentation Febuary 9 th , 2010

N-Heterocyclic Carbene-Catalyzed Generation of Homoenolates: Historical Perspective and Contributions of Jeffrey W. Bode. Literature Presentation Febuary 9 th , 2010. Presented by Louis-Philippe Beaulieu. Thiamine: a Naturally Occuring NHC Precursor.

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Literature Presentation Febuary 9 th , 2010

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  1. N-Heterocyclic Carbene-Catalyzed Generation of Homoenolates: Historical Perspective and Contributions of Jeffrey W. Bode. LiteraturePresentation Febuary 9th, 2010 Presented by Louis-Philippe Beaulieu

  2. Thiamine: a Naturally Occuring NHC Precursor Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726.

  3. Thiamine: a Naturally Occuring NHC Precursor Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726.

  4. Thiamine: a Naturally Occuring NHC Precursor Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726.

  5. Mechanistic Insights Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726. Krohnke, F. Angew. Chem.1953, 65, 605-607

  6. Mechanistic Insights Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726. Schenkel, H.; Schenkel-Rudin, M. Helv. Chim. Acta 1948, 31, 924-929.

  7. Mechanistic Insights Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726. Schenkel, H.; Schenkel-Rudin, M. Helv. Chim. Acta 1948, 31, 924-929.

  8. Mechanistic Insights Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726. Lapworth, A. J. Chem. Soc., Trans., 1903, 83, 995-1005.

  9. Mechanistic Insights Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726. Lapworth, A. J. Chem. Soc., Trans., 1903, 83, 995-1005.

  10. Mechanistic Insights Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726.

  11. Mechanistic Insights Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726.

  12. Mechanistic Insights Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726.

  13. Mechanistic Insights Breslow, R. J. Am. Chem. Soc. 1958, 80, 3719-3726.

  14. Isolable NHCs: Contributions of Arduengo Arduengo, A. J.; Harlow, R. L.; Kline, M. J. Am. Chem. Soc. 1991, 113, 361-363. Arduengo, A. J.; Dias, H. V. R.; Harlow, R. L.; Kline, M. J. Am. Chem. Soc. 1992, 114, 5530-5534.

  15. Asymmetric Benzoin Reaction Enders, D.; Kallfass, U. Angew. Chem., Int. Ed. 2002, 41, 1743-1745.

  16. Asymmetric Benzoin Reaction Enders, D.; Kallfass, U. Angew. Chem., Int. Ed. 2002, 41, 1743-1745.

  17. Asymmetric Cross-Benzoin Reaction Enders, D.; Niemeier, O.; Balensiefer, T. Angew. Chem., Int. Ed. 2006, 45, 1463-1467.

  18. Asymmetric Cross-Benzoin Reaction Takikawa, H.; Hachisu, Y.; Bode, J. W.; Suzuki, K. Angew. Chem., Int. Ed. 2006, 45, 3492-3494.

  19. Exploration of Other Reactivity Modes of the Breslow Intermediate Sohn, S. S.; Rosen, E. L.; Bode, J. W. J. Am. Chem. Soc. 2004, 126, 14370-14371.

  20. Jeffrey W. Bode Jeffrey studied chemistry and philosophy at Trinity University in San Antonio, Texas and worked in the research group of Prof. Michael P. Doyle. He began his graduate studies in organic chemistry at the California Institute of Technology in 1996. In 1998, he moved with his research advisor, Prof. Erick M. Carreira, to the Swiss Federal Institute of Technology (ETH) in Zürich, Switzerland, where he completed his Doc. Nat. Sci. in 2001. Following a two year Japan Society for the Promotion of Science Postdoctoral Fellowship with Prof. Keisuke Suzuki at the Tokyo Institute of Technology in Tokyo, Japan, he joined the Department of Chemistry and Biochemistry at UC-Santa Barbara in 2003. In Fall 2007, he moved to the University of Pennsylvania as Associate Professor in the Department of Chemistry.

  21. Synthesis of γ-Butyrolactones Sohn, S. S.; Rosen, E. L.; Bode, J. W. J. Am. Chem. Soc. 2004, 126, 14370-14371.

  22. Synthesis of γ-Butyrolactones Sohn, S. S.; Rosen, E. L.; Bode, J. W. J. Am. Chem. Soc. 2004, 126, 14370-14371.

  23. Synthesis of γ-Butyrolactones Sohn, S. S.; Rosen, E. L.; Bode, J. W. J. Am. Chem. Soc. 2004, 126, 14370-14371.

  24. Synthesis of γ-Butyrolactones: Contribution of Glorius Burstein, C.; Glorius, F. Angew. Chem., Int. Ed. 2004, 43, 6205-6208.

  25. Synthesis of γ-Butyrolactones: Contribution of Glorius Burstein, C.; Tschan, S.; Xie, X.; Glorius, F. Synthesis 2006, 2418-2439.

  26. Formation and Esterification of Activated Carboxylates Sohn, S. S.; Bode, J. W. Org. Lett. 2005, 7, 3873-3876.

  27. Formation and Esterification of Activated Carboxylates Sohn, S. S.; Bode, J. W. Org. Lett. 2005, 7, 3873-3876.

  28. Formation and Esterification of Activated Carboxylates Sohn, S. S.; Bode, J. W. Org. Lett. 2005, 7, 3873-3876.

  29. Formation and Esterification of Activated Carboxylates Sohn, S. S.; Bode, J. W. Org. Lett. 2005, 7, 3873-3876.

  30. Synthesis of β-Hydroxyesters from Epoxyaldehydes Chow, K. Y.-K.; Bode, J. W. J. Am. Chem. Soc. 2004, 126, 8126-8127.

  31. Synthesis of β-Hydroxyesters from Epoxyaldehydes Chow, K. Y.-K.; Bode, J. W. J. Am. Chem. Soc. 2004, 126, 8126-8127.

  32. Synthesis of β-Hydroxyesters from Epoxyaldehydes Chow, K. Y.-K.; Bode, J. W. J. Am. Chem. Soc. 2004, 126, 8126-8127.

  33. Synthesis of β-Hydroxyesters from Epoxyaldehydes Chow, K. Y.-K.; Bode, J. W. J. Am. Chem. Soc. 2004, 126, 8126-8127.

  34. NHC-Mediated Opening of Chiral Formylcyclopropanes Sohn, S. S.; Bode, J. W. Angew. Chem., Int. Ed. 2006, 45, 6021-6024.

  35. NHC-Mediated Opening of Chiral Formylcyclopropanes Sohn, S. S.; Bode, J. W. Angew. Chem., Int. Ed. 2006, 45, 6021-6024.

  36. NHC-Mediated Opening of Chiral Formylcyclopropanes Sohn, S. S.; Bode, J. W. Angew. Chem., Int. Ed. 2006, 45, 6021-6024.

  37. NHC-Mediated Opening of Chiral Formylcyclopropanes Bode, J. W.; Sohn, S. S. J. Am. Chem. Soc. 2007, 129, 13798-13799.

  38. NHC-Mediated Opening of Chiral Formylcyclopropanes Bode, J. W.; Sohn, S. S. J. Am. Chem. Soc. 2007, 129, 13798-13799.

  39. Catalytic Redox Amidations of Enals Bode, J. W.; Sohn, S. S. J. Am. Chem. Soc. 2007, 129, 13798-13799.

  40. Enantioselective Azadiene Diels-Alder Reactions He, M.; Struble, J. R.; Bode, J. W. J. Am. Chem. Soc. 2006, 128, 8418-8420.

  41. Enantioselective Azadiene Diels-Alder Reactions He, M.; Struble, J. R.; Bode, J. W. J. Am. Chem. Soc. 2006, 128, 8418-8420.

  42. Enantioselective Azadiene Diels-Alder Reactions He, M.; Struble, J. R.; Bode, J. W. J. Am. Chem. Soc. 2006, 128, 8418-8420.

  43. Enantioselective Oxodiene Diels-Alder Reactions He, M.; Uc, G. J.; Bode, J. W. J. Am. Chem. Soc. 2006, 128, 15088-15089.

  44. Enantioselective Oxodiene Diels-Alder Reactions He, M.; Uc, G. J.; Bode, J. W. J. Am. Chem. Soc. 2006, 128, 15088-15089.

  45. Cyclopentene Formation Through Benzoin-Oxy-Cope Reactions Chiang, P.-C.; Kaeobamrung, J.; Bode, J. W. J. Am. Chem. Soc. 2007, 129, 3520-3521.

  46. Cyclopentene Formation Through Benzoin-Oxy-Cope Reactions Chiang, P.-C.; Kaeobamrung, J.; Bode, J. W. J. Am. Chem. Soc. 2007, 129, 3520-3521.

  47. Cyclopentene Formation Through Benzoin-Oxy-Cope Reactions Chiang, P.-C.; Kaeobamrung, J.; Bode, J. W. J. Am. Chem. Soc. 2007, 129, 3520-3521.

  48. NHC-Mediated Bicyclo-β-Lactam Formation He, M.; Bode, J. W. J. Am. Chem. Soc. 2007, 130, 418-419.

  49. NHC-Mediated Bicyclo-β-Lactam Formation He, M.; Bode, J. W. J. Am. Chem. Soc. 2007, 130, 418-419.

  50. NHC-Mediated γ-Lactam Formation Rommel, M.; Fukuzumi, T.; Bode, J. W. J. Am. Chem. Soc. 2008, 130, 17266-17267.

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