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The Structure and Function of Macromolecules. Introduction and Carbohydrates. What is a macromolecule. Macro = large There are 4 groups of molecules that are found in large quantities in our bodies. The molecules themselves are large. They are: Carbohydrates Proteins Nucleic Acids Lipids.
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The Structure and Function of Macromolecules Introduction and Carbohydrates
What is a macromolecule • Macro = large • There are 4 groups of molecules that are found in large quantities in our bodies. • The molecules themselves are large. • They are: • Carbohydrates • Proteins • Nucleic Acids • Lipids
What is a macromolecule? • Macromolecules are polymers. • Poly- = many • -mer = unit • Polymers are long molecules built by linking repeating building blocks or units in a chain. • Held together with covalent bonds.
H2O HO H HO H HO H How are macromolecules made? • Dehydration synthesis or condensation synthesis. • Hydrogen is removed from one subunit while hydroxyl group is removed from the adjacent subunit. • They join together to form a water molecule.
H2O HO H H HO H HO How are macromolecules broken apart? • Process is called hydrolysis. • A molecule of water is used. • The water molecule is split apart into the H+ and OH- ions. • H+ attaches to one end and the OH- attaches to the other.
CH2OH O H H H OH H OH HO H OH Carbohydrates
Carbohydrates • General formula = CH2O • 1 C: 2H : 1 O • Monomer = sugars • Names tend to end in -ose • Functions • Energy • Energy storage • Raw materials • Structural materials
Ways of Classifying Sugars • Location of the carbonyl group aldehyde ketone
H O C CH2OH CH2OH C OH O H H O H H H OH H OH H C H HO OH HO HO H H H OH OH H Glyceraldehyde Glucose Ribose Ways of Classifying Sugars • Numbers of Carbons • 3 carbons = triose • 5 carbons = pentose • 6 carbons = hexose 6 5 3
Ways of Classifying Sugars • Special arrangements In Starch In Cellulose • Isomers of glucose • Think about the relationship of structure and function
Another example of special arrangements • Another example comparing glucose and galactose
3 Classes of Carbohydrates • Monosaccharides • Simple • 1 sugar • Examples – fructose, ribose, glucose • Disaccharides • 2 sugars • Joined together with a glycosidic linkage Sucrose Glucose Fructose
Classes of Carbohydrates • Examples of Dissacharides • Sucrose = glucose + fructose This is table sugar. • Maltose = glucose + glucose This is used in making malt beverages. • Lactose = galactose + glucose This is milk sugar.
Classes of Carbohydrates • Polysaccharides • Many sugars. • Examples • Starch: Storage polysaccharide in plants • Simplest = amylose (unbranched) • More complex starch = amylopectin (branched)
Polysaccharides continued • Glycogen • Storage polysaccharide in animals • Is branched • Stored as glucagon in the liver • Cellulose • Structural polysaccharide in plants • Found in plant cell walls • Also called fiber • Animals can not break it down
Polysaccharides continued • Chitin • Structural polysaccharide • Found in the exoskeleton of arthropods and cell walls of fungi.
Starch vs Glycogen Starch Plants Energy Storage Glycogen Animals
Starch vs Cellulose Easy to digest Difficult to digest