1 / 16

Tridax procumbence- A Potent Blood Coagulant

Tridax procumbence- A Potent Blood Coagulant. Futane S.M ., Mohite N.R., Nakat J.M. Shri. Shivaji college of Agri-Biotechnology, Amravati. INTRODUCTION -.

nascha
Download Presentation

Tridax procumbence- A Potent Blood Coagulant

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Tridaxprocumbence-A Potent Blood Coagulant Futane S.M., Mohite N.R., Nakat J.M. Shri. Shivaji college of Agri-Biotechnology, Amravati

  2. INTRODUCTION - Tridax procumbence is a widespread weed,commonly known as coat button in english,ekdandi or kambarmodi in marathi,ghamra in hindi and jayantiveda in sanskrit Botanical classification: • Kingdom: Plantae • Division: Magnoliophyta • Class: Magnoliopsida • Order: Asterales • Family: Asteraceae • Tribe: Heliantheae • Genus:Tridax • Species: T. Procumbens

  3. ABSTRACT Tridax procumbence is a species of flowering plant in a daisy family.It occurs in tropical as well as subtropical regions,in all the seasons. It exhibits antiseptic,insecticidal and hair growth promoting properties.More commonly the plant leaves are used to check haemorrhage from cuts,brucies,wounds. It also reported to have various pharmacological effects and antimicrobial activity against bacteria,hence prevent the infection and stimulate wound healing.

  4. KEYWORDS Tridaxprocumbence,blood coagulation,aspartic acid,marker enzymes,alanine transamylase.

  5. CHEMICAL COMPOSITION AND THEIR PHYSIOLOGICAL RESPONSE. • Stigmasterol -antiinflametory property • Betasitosterol-antiinflametory property • Calcium-required for coagulation factors to bind to phospholipids. • Phospholipids-required for tenase and prothrombinase to function. • Marker enzymes –Helps in conversion of fibrinogen to fibrin. (aspartate,transaminase, lactate dehydrogenase, alkaline phosphatase)

  6. MECHANISM OF BLOOD COAGULATION • Blood clotting comes under the concept of haemostasis.It is the major defence mechanism against the blood loss and occurs due to different substances mainly glycoproteins synthesized by the liver. • It involves two pathways A)Extrinsic Pathway :It is the initial process in the clotting and involves factors that are not present in the blood. B)Intrinsic Pathway :It involves the series of reaction participated by the factors present in the blood. The two pathways are not independent but they are coupled together to convert protrombin to thrombin and fribrinogen to fibrin clot.

  7. Important factors responsible for blood coagulation. • Fibrinogen:forms clot • Prothrombin:it activates protein c and platelets. • Tissue factor:co factor of prothrombin • Calcium:helps to bind the coagulation factor to phospholipids. • Christmas factor:forms tenase complex with antihaemophillic factors • Hageman factor :activates plasma protein. • High mol.Wt kininogen factor :support activation of hageman’s factor • Staurt prower factor: forms prothrmbinase complex with labile factor • Generation factor: precipitates in final common clotting pathway. • Fibrin stabilizing factor: carried out cross links of fibrins.

  8. Diagram

  9. MATERIAL REQUIRED Sterile dry powder of Tridax procumbence,fresh blood sample without anticoagulant,test tubes,stopwatch,etc.

  10. METHOD • Take 2 ml of fresh blood sample in two test tubes without adding any anticoagulant. • Take one test tube as control and other as test sample. • Add 200mg of sterile dry powder of Tridax procumbence in test sample. • Do not add Tridax procumbence powder in control. • Note coagulation time of both samples.

  11. OBSERVATION Test sample clots earlier than control.

  12. RESULT Dry powder of Tridax procumbencehelps in faster blood coagulation

  13. CONCLUSION Tridax procumbence have great medicinal properties and can be used for – • Wound healling • Haemophillic disorders • Bleeding disorders • Antiinflamatory property • Primary source of treatment in tribal areas where medical supervision is not available.

  14. References • Dravya-gun vigyan-Dharmadhikari • Textbook of pathology-harshmohan • Textbook of biochemistry and human biology-J.P.Talwar • Biochemistry-satyanarayan • www.biologyforum.com • www.sciencedictionary.com • www.botanica.com

  15. Thank You.

  16. This powerpoint was kindly donated to www.worldofteaching.com http://www.worldofteaching.com Is home to well over a thousand powerpoints submitted by teachers. This a free site. Please visit and I hope it will help in your teaching

More Related