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Carbohydrates. Remember “-ose” suffix C, H, O in a 1:2:1 ratio Monomers are MONOSACCHARIDES glucose, fructose, galactose, ribose C 6 H 12 O 6 or (CH 2 O) n /n= 3-8 Isomers: same chemical (molecular) formula but different structural formulas. Monosaccharides. Glucose
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Carbohydrates • Remember “-ose” suffix • C, H, O in a 1:2:1 ratio • Monomers are MONOSACCHARIDES • glucose, fructose, galactose, ribose • C6H12O6 or (CH2O)n /n= 3-8 • Isomers: same chemical (molecular) formula but different structural formulas
Monosaccharides • Glucose • primary, short term energy source • made during photosynthesis
Monosaccharides • Fructose • plant sugar • sweet
Monosaccharides • Ribose • C5H10O5 • Found in ribonucleic acid (RNA) • Deoxyribose • missing an oxygen • Found in DNA
Isomers • Same chemical formula (number and type of atoms) • Different structural formulas (arrangement of atoms in space)
Disaccharides • Two monosaccharides joined together by dehydration synthesis(2 sugars) • Sucrose--table sugar--fructose + glucose • Lactose--milk sugar--glucose + galactose • Maltose--malt sugar--two glucose
Polysaccharides • Complex • Made of many monosaccharides (glucose is most common) • Condensation Rxn • Glycogen, Chitin (animals) • Starch, Cellulose (plants)
Polysaccharides--Glycogen • Branched chain of glucose monomers • Intermediate energy source for animals • Stored in liver and muscles • Liver converts to glucose through hydrolysis when quick energy is needed
Polysaccharides--Starch • Branching or spiral chain of glucose monomers • Plant storage molecule--energy reserve
Polysaccharides--Cellulose H-Bond • Long straight chains of glucose monomers • Chains laid side by side, connected by Hydrogen bonds • Structural carbohydrate--does not provide energy • “Fiber” • Most abundant carb
LIPIDS • C, H, O • Large numbers of C’s and H’s/few O’s • Fats, oils, waxes, steroids • NONPOLAR/HYDROPHOBIC • Excess energy storage (2x’s carbs), insulation, padding and shape, vitamin storage, structural, chemical messengers
Lipid Monomers • Glycerol--3 carbon chain • Fatty acid chain--hydrocarbon (C and H) with a fatty acid (carboxyl group) COOH attached Fatty Acid Chain glycerol
Triglycerides • Type of lipid • glycerol + 3 fatty acids • saturated or unsaturated
(+H2O) Dehydration Syntheis (-H2O)
Unsaturated Triglyceride • Hydrocarbon portion has one or more double or triple bonds • bent chain (double and triple bonds in FA Chain • plants/liquid at room temperature
Saturated Fatty Acid • Single bonds in hydrocarbon chain • Straight chains • Animals/solid at room temperature • Atherosclerosis (plaques in arteries)
Straight Chain Bent Chain kinks
Hydrogenation • The process of converting naturally unsaturated oils into saturated ones through the forced addition of hydrogens. • Gets rid of double/triple bonds to create a solid, straight chained fat • Peanut butter and margarine
WAXES • Long chain fatty acids + an alcohol group • long chain makes it very waterproof • Plants use waxes as coating--cuticle--to keep from drying out • Animals use wax as protection against microorganisms--ears
PHOSPHOLIPIDS • Almost like a triglyceride except a phophate group takes the place of one fatty acid chain • Glycerol + 2 FA chains + 1 phosphate group • Head-phosphate-polar • Tail-FA chain-nonpolar
STEROIDS • Four fused carbon rings • 3 six sided, 1-5 sided, and an R goup (variety) • No glycerol or fatty acid • Nonpolar property makes them a lipid R’
PROTEINS • C, H, O, N • Monomer is amino acid (20 different) • Condensation Rxn • Amino Acid has five parts • amine group (NH2), central carbon, carboxyl group (COOH), single hydrogen, R group • R (radical group) determines type of amino acid and properties
Amino Acid Monomer Single H Central C R group R group different in each Amino Acid: 20 Different R groups
Formation of a Peptide (Protein) • Peptide bonds form during condensation • Covalent in nature
Levels of Protein Organization • Primary Structure • straight chain amino acid sequence
Secondary Structure • helical • fomation of hydrogen bonds between amino acids of one primary chain
Tertiary Structure • folding of primary structure occurs • various interactions between atoms of amino acids
Quaternary Structure • association of two or more peptides (proteins) with the primary structure
Functions of Proteins • Used in cell membrane--transport • Enzymes--Catalysts (-ase suffix) • Antibodies--immune system • Hormones • Venom • Structural--muscles
Lock and Key Model of Enzyme • Substrate is reactant being catalyzed (changed) • Fits into enzyme like key fits into lock • Weakening of chemical bonds • Enzymes not altered and can be reused • Substrate specific
How a Poison Works • Poison molecule blocks enzyme so it cannot recognize its substrate • Example: locoweed poisoning in livestock
Denaturing • Heat or weak acid can destroy Hydrogen bonds/inactivates enzymes • tertiary structure will uncoil (denaturation) • vinegar (acetic acid) can “cook” albumen (white) of egg without heat • proteins in raw fish denatured by citric acid in lime or lemon juice • hemolytic proteins at site of snakebite can be denatured by electrical discharge (stun gun)
Nucleic Acids • Polymers that store genetic information • Monomers are nucleotides • 3 parts: phosphate group, sugar (ribose or deoxyribose), and one of four nitrogen bases • DNA: deoxyribose + phosphate + base (adenine, guanine, thymine, cytosine) • RNA: ribose + phosphate + base (adenine, guanine, uracil, cytosine) • Bonding (A-T or A-U; C-G)
C5H10O5 C5H10O4
Purines (2 rings) adenine, guanine Pyrimidines (1 ring) cytosine, thymine, uracil Nitrogen Base Types
Rosalyn Franklin • First to recognize the helix shape of DNA using X-ray crystallography • Her work was passed on to James Watson and Francis Crick who used it to determine the detailed structure of DNA • Never given official credit for her contribution to the study • Died at age 37 from cancer
James Watson and Francis Crick • Used Franklin’s information to determine details of DNA • Won Nobel Prize for discovery in 1962
VERY Helpful Websites • www.emc.maricopa.edu • Choose Biology, then #3 Chem II: Water and Organic Molecules • www.waynesword.palomar.edu/bio100 • Choose Chemicals of Living Systems