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Update in direct restoratives. Caries incidence globally. Dental caries is still a major public health problem to most countries of the world Petersen, Baez, Kwan & Ogawa 2009 Future Use of Materials for Dental Restoration
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Caries incidence globally • Dental caries is still a major public health problem to most countries of the world Petersen, Baez, Kwan & Ogawa 2009 Future Use of Materials for Dental Restoration Report of the meeting convened at WHO HQ, Geneva, Switzerland.
“ Dentists spend approximately 70% of their time replacing restorations ” Minimal intervention dentistry: a review. FDI Commission Project. Tyas et al 2000
DENTAL AMALGAM • bonded vs non bonded AR • longevity of AR • cavity size • operator experience • comparison with PCR • issue of mercury toxicity
Bonded vs nonbonded AR • Longevity bonded AR > nonbonded AR ?
Adhesively bonded versus non-bonded amalgam restorations for dental caries • randomized clinical trials • split mouth or paired tooth • Class I, II, or V restorations • with any adhesive • minimum follow up of 2 years Fedorowicz et al, Cochrane Database Syst Rev 2009 ; CD007517
Adhesively bonded versus non-bonded amalgam restorations for dental caries • “ …no evidence to show a difference in amalgam restoration survival on the basis of whether the restoration was adhesively bonded or not.” Fedorowicz et al, Cochrane Database Syst Rev 2009 ; CD007517
How long do direct restorations placed within the general dental services in England and Wales survive ? • 80 000 subjects, 503 965 restorations • 11-year duration • AR mainly for posterior load bearing CR for Class III and IV GIC for Class V Burke & Lucarotti 2009, 206:E2, discussion 26-7
How long do direct restorations placed within the general dental services in England and Wales survive ? • small AR showed the best 10-year survival rates ( 58%) • large MOD AR showed poorer 10-year survival rates ( 43% ) • pin placement associated with reduced survival time • CR including incisal angle – reduced survival by 2 years • GIC – 10-yr survival rate of 38% Burke & Lucarotti 2009, 206:E2, discussion 26-7
Longevity of restorations • AR – 16 years irregardless of restoration classification • CR – 6 years with Class 2 showing lowest longevity • High caries risk – reduced CR longevity compared to low or moderate caries Sunnegardh-Gronberg et al 2009
Longevity of restorations • Operator experience dentists with 15 or more years of experience provided restorations with > longevity for both AR and CR Sunnegardh-Gronberg et al 2009
1997 Consensus Statement on Dental Amalgam • ‘ No controlled studies have been published demonstrating systemic adverse effects from amalgam restorations ” • ‘ .... the small amount of mercury released from amalgam restorations, especially during placement and removal, has not been shown to cause any …adverse health effects. ’ FDI World Dental Federation & WHO
1998 • Major review of the literature • “ based on available scientific information, amalgam continues to be a safe and effective restorative material “ • “ there currently appears to be no justification for discontinuing the use of dental amalgam ” ADA’s Council on Scientific Affairs
2004 • Expert panel reviewed literature from 1996 – 2003 • “ the current data are insufficient to support an association between mercury release from dental amalgam and various complaints that have been attributed to this restorative material. ”
2006 • 2 independent clinical trials • “ there were no statistically significant differences in adverse neuropsychological or renal effects observed over the 5-year period in children whose caries are restored using dental amalgam or composite materials …………….
2006 • ………. “ children ………..did not, on average, have statistically significant differences in neurobehavioral assessments in nerve conduction velocity when compared with children who received resin composite materials or amalgam ”
2006 • “ ……….amalgam should remain a viable dental restorative option for children ” Journal of the American Medical Association Environmental Health Perspectives
Environmental concerns “ If environmental contamination by mercury containing waste from dental practices is not cut down to very low levels, then it is likely to be the main reason for government action against the use of amalgam in the future ” Eley 1997
2008 • “ …dental amalgams are effective and safe, both for patients and dental personnel and also noted that alternative materials are not without clinical limitations and toxicological hazards ” Scientific Committee of the European Commission
2009 • Literature review from 2004 – 2009 • “ the scientific evidence supports the position that amalgam is a valuable, viable and safe choice for dental patients ” ADA Council on Scientific Affairs
2009 • classified encapsulated dental amalgam as a class II medical device • “ …..the material is a safe and effective restorative option for patients ” FDA, US
2009 “ …dental amalgam remains a dental restorative material of choice, in the absence of an ideal alternative and lack of evidence of alternatives as a better practice. If dental amalgam were to be banned, a better and more long-lasting replacement would be needed than the materials available to date ….”
2009 “ …. while the harmful effects of mercury on health and the environment are recognized, the possible adverse effects of alternative materials require further research and monitoring. Providing the best care possible to meet patients’ needs should be of paramount importance. ”
2009 “… complete ban may not be realistic, practical and achievable. It may be prudent to consider ‘phasing down’ instead of ‘phasing out’ of dental amalgam at this stage ” Future use of materials for dental restoration Report of the meeting convened at WHO HQ, Geneva, Switzerland. 2009
Ethical issues • correlate amalgams to adverse health symptoms/disease • removal of amalgams to provide placebo effect • removal of amalgams at patient’s request • amalgam - free practice
Minimata Convention on Mercury Treaty • ........treaty to rein in the use and emission of health-hazardous mercury • amid pressure from dentist groups, the treaty also did not provide a cut-off date for the use of dental fillings using mercury amalgam, but did agree that the product should be phased down. UN Environmental Program ( UNEP) Geneva , 19th Jan 2013
The World Alliance for Mercury-Free Dentistry called for phasing out dental amalgam by 2025 and by 2018 for baby teeth.
“ majority of patients prefer a tooth – coloured material ( composite ), even when informed that the clinical longevity will be shorter than that of amalgam ” Espelid et al 2006
DIRECT TOOTH COLOURED RESTORATIVE MATERIALS
classical classical Glass Ionomer Cements Composite Resins GI – RESIN HYBRIDS RMGIC PM COMP RESIN
GIC Resin Modified GIC Antonucci et al 1988, Mitra 1988 GIC + monomers + photoinitiators
Issues - RMGIC • retention • margins • wear, loss of anatomic form • colour change • fluoride leaching
RMGIC • Clinical evaluations of resin-modified glass-ionomer cements Sidhu, Dent Mater, 2010 , 26 (1) : 7-12 • Clinical performance of cervical restorations—A meta-analysis Heintze et al, Dent Mater, 2010, 26 ( ) : 993-1000
Retention • retention rate range from 87.5% - 100% • 2-step SE > 3-step E & R > GIC > RMGIC > 2-step E & R > PMCR > 1-step SE
anatomic form and wear • occurs in the mid- to long term
secondary caries • No secondary caries was found in carious and non carious cavities for up to 5 years. Neo et al 1996 Abdalla et al 1997 van Dijken et al 1999 Folwaczmy et al 2001 Loguercio et al 2003
Caries preventive effect of GIC and RMGIC • 4 out of 220 studies • RMGIC restorations remain as free of recurrent caries as did conventional GIC restorations Mickenautsch et al. Absence of carious lesions at margins of GIC and resin-modified GIC restorations. A systematic review . Eur J Prosthodont Rest Dent 2010:18:139-145
colour stability initial colour may be acceptable but changes over time
classical classical Glass Ionomer Cements Composite Resins GI – RESIN HYBRIDS RMGIC PM COMP RESIN
Composite Resins Developments of CR • materials • bonding systems • light systems
Material what’s new ?? • monomer /matrix • filler
Monomers • traditionally bis-GMA ( Bowen 1960 ) + TEGDMA • UDMA ( Foster and Walker 1974 ) and modified UDMA
NEW - monomers • reduce polymerization shrinkage/stress • SiloranesWeinmann et al 2005 • modified UDMA – increased molecular weight egKalore ( GC ), Venus ( Kulzer) N’Durance ( Septodent) • Ormocerseg Definite ( Degussa )Wolter et al 1994
Microhybrid and nanohybrid CR • improved strength, handling & polishability Ritter 2005 Watanabe et al 2008 • reduced wear Yap et al 2004 Yesil et al 2008
NEW – modify fillers Add • polymer nonofibers, glass fibres, fused silica fibres and titaniananoparticles • dicalcium/tetracalcium phosphate nanoparticles • antibacterial and remineralising agents eg fluoride, chlorhexidine, zinc oxide or quaternary ammmoniumpolyethyleneiminenanoparticles, MDPM monomer
NEW • Nanocomposites • incorporate calcium fluoride nanoparticles into dental resins • high levels of calcium phosphate and fluoride release achievable at low filler particle levels due to high surface areas of nanoparticles • addition of nanoparticles do not affect mechanical properties of resin Xu et al 2010
Bulk fill CR • high depth of cure (4-5 mm) • reduce incremental placement • less porosities • less time • use below the restoration (flowable) or as a restorative (sculptable) material
Bulk Fill CR • Flowables • Surefil SDR Flow Dentsply • X-tra Base Voco • Venus Bulk Fill Heraeus Kulzer • FiltekBulk Fill 3M ESPE • Sculptables • Tetric N-Ceram Bulk Fill Ivoclar/Vivadent • X-tra Fil Voco • QuiXfil Dentsply • SonicFill Kerr
How did we achieve the reduction in polymerization stress? ANSWER: • The kinetics of the radical polymerization is regulated • As the modulus development is slower less polymerization stress builds up. • Call it a chemical soft start polymerization if you like.
Any (!) cap composite* SDR™ SDR™ Filling Technique Perfect Compatibility with metharylate-based bonding and capping composites * EsthetX HD, CeramX, Spectrum TPH 3, Filtek Supreme, Tetric EvoCeram, Artemis, Z100, Point4, Venus, Enamel HFO, Herculite, Premise, etc ... but not Filtek Silorane