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Maternal care: Licking & grooming pups. Adult ‘memory’ of maternal care. 5HT release. Hippocampus. Negative feedback. Chromatin remodeling. cAMP, PKA. (DeMethylation of NGFi binding site). NGFi transcript. factor. Long-term up regulation of GC mRNA expression. Glucocorticoid receptors.
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Maternal care: Licking & grooming pups Adult ‘memory’ of maternal care 5HT release Hippocampus Negative feedback Chromatin remodeling cAMP, PKA (DeMethylation of NGFi binding site) NGFi transcript. factor Long-term up regulation of GC mRNA expression Glucocorticoid receptors Stress Adrenal glands Hypothalmic CRF release Pituitary, ACTH Glucocort. release