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Toxoplasma Gondii

Toxoplasma Gondii. Classification toxoplasma gondii Phylum :- Protozoa Class :- Sporozoa Order :- Eimeriina Family :- Toxoplasmatidae Genus :- Toxoplasma gondii. Introduction

nichole-oliver
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Toxoplasma Gondii

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  1. Toxoplasma Gondii

  2. Classification toxoplasma gondii Phylum :- Protozoa Class :- Sporozoa Order :- Eimeriina Family :- Toxoplasmatidae Genus :- Toxoplasma gondii

  3. Introduction Toxoplasma gondii is an intestinal coccidium that parasitizes members of the cat family as definitive hosts and has a wide range of intermediate hosts. Infection is common in many warm-blooded animals, including humans. In most cases infection is asymptomatic, but devastating disease can occur.

  4. Morphology and life cycle 1-Trophozoite :- 2- Cyst :- In Intermediate hosts 3- Oocyst :- 4- Schizonte :- 5- Gametogenic:- In Definitive hosts

  5. FIGURE -1- Trophozoite

  6. FIGURE -2- Sexual states of Tgondii

  7. Figure-3- Toxoplasma gondii is transmitted.

  8. Cysts ingested by cat Oocyst in feces In feces Sporoblast sporocyst Sporozoites oocust Development Mutureoocyst Zygote Reproduction (endodyogeny) مضيف وسطي ♀♂ Development Tropho Ingested by cat or any animals Ep.cells of the int.of cat Different organs Stomach Blood Sporozoite //// ////

  9. Pathogenesis Congenitally : A- Intra cerebral calci fication :تكلس داخل المخ B- Chorioretinitis :التهاب المشيمية والشبكية C- Hydro cephalus :تجمع الماء في الرأس D- Encephalitis :التهاب الدماغ Acquired A- Lymphodenitis : ( حمى – فقر دم – انخفاض ضغط الام عضلية ) التهاب لمفاوي B- Acute infection Example :- * Encephalomyelitisالتهاب السحايا * Pneumonitis التهاب الرئة * Nyo carditis التهاب العضلة القلبية C- Chronic Toxoplasmosis (صداع-فقدان الوزن-ضعف عضلي)

  10. Diagnosis • Diagnosis is based on serology • by :- * Inhibition Fluorecent anti body test . • *ELISA test • *Indirect haemaglutination test • And on histologic examination of tissue . • Treatment :- • 1-Pyrimethamine 25mg every day (3-4) weaks . • 2- Sulfonamides . • 3- Sulfadiazine . • 4- Sulfamethazine and sulfamerazine

  11. Figure-4- Girl with hydrocephalus due to congenital toxoplasmosis.

  12. Figure-5- Girl with hydrocephalus due to congenital toxoplasmosis.

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