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Granulation. done to improve flow properties of the mix improve compression properties of the mix prevent segregation of components in powder mix reduce production of toxic dust reduce possibility of ‘cake’ formation increase convenience of transport. Granulation.
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Granulation • done to • improve flow properties of the mix • improve compression properties of the mix • prevent segregation of components in powder mix • reduce production of toxic dust • reduce possibility of ‘cake’ formation • increase convenience of transport
Granulation • particle bonding mechanisms • adhesion and cohesion forces in immobile liquid films • interfacial forces in mobile liquid films • solid bridges • attractive forces between solid particles
Granulation • Wet granulation equipment • 3 main types • shear granulators • high speed mixer/granulators • fluidized bed granulators • shear granulator
Wet Granulation • high speed mixer/granulator
Wet Granulation fluidized bed granulator
Wet Granulation • other more specialized granulators • spray driers
Wet Granulation • pelletizers
Dry Granulation • Dry granulation equipment • sluggers • roller compactors