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Hand Foot and Mouth Disease. Danielle Hann ST2 GPVTS 2010. Hand foot and mouth. Typically children <10 years Commonly <4 years Common to have outbreaks. Causes. Most common is coxsackie A16 Less common but more serious Enterovirus 17. Incubation/Infectivity. Incubation 3-5 days
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Hand Foot and Mouth Disease Danielle Hann ST2 GPVTS 2010
Hand foot and mouth • Typically children <10 years • Commonly <4 years • Common to have outbreaks
Causes • Most common is coxsackie A16 • Less common but more serious Enterovirus 17
Incubation/Infectivity • Incubation 3-5 days • Infectious <7 days • Transmission via • Direct contact of secretions or fluid in blisters • Faeco-oral • Vertical spread
Signs/Symptoms • Prodrome – 12-36 hours • Sore throat • Fever • Mouth • 2-8mm macules and papules progressing to vesicles • Skin • Macules and papules on hands and feet • Buttocks and groin may also be affected
Treatment • Reassurance • Prevention of transmission • Fluid intake • Analgesia • Oral • Topical • School exclusion • Until symptoms resolve, blisters dried
Complications • Dehydration • Secondary bacterial infection • EV17 • Encephalitis • Aseptic meningitis • Acute flaccid paralysis • Fatal neurogenic pulmonary oedema
Referral • Dehydration • Urgently if neurological complications • Severe headache, persistent fever, myoclonic jerks • Persistent oral ulcers • Unexplained oral ulcers >3 weeks
Prognosis • Coxsackie A16 • Nearly always resolve 5-10 days • Immunity to further infection but can recur with different virus