1 / 21

Set up Cornell Notes on pg. 11 Topic: 8.7 Mutations Essential Question :

8.7 Mutations. 2.1 Atoms, Ions, and Molecules. Set up Cornell Notes on pg. 11 Topic: 8.7 Mutations Essential Question : Explain why a frameshift mutation has a greater effect than do point mutations. Explain why a frameshift mutation has a greater effect than do point mutations.

npalmore
Download Presentation

Set up Cornell Notes on pg. 11 Topic: 8.7 Mutations Essential Question :

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 8.7 Mutations 2.1 Atoms, Ions, and Molecules • Set up Cornell Notes on pg. 11 • Topic: 8.7 Mutations • Essential Question: • Explain why a frameshift mutation has a greater effect than do point mutations. • Explain why a frameshift mutation has a greater effect than do point mutations. KEY CONCEPT Mutations are changes in DNA that may or may not affect phenotype

  2. Points to Ponder • P.10 Point Mutation Frameshift Mutation

  3. Points to Ponder (Top of p. 10) • What do you think of when you hear the word “mutation”? • Are they always bad? • Give me an example

  4. Mutations?

  5. Mutations (1m13s)

  6. KEY CONCEPT Mutations are changes in DNA that may or may not affect phenotype.

  7. Not all mutations are bad, but most do have negative effects What mutations do you notice here? Why might these be problematic?

  8. A mutation is a change in an organism’s DNA. • Many kinds of mutations can occur, especially during replication.

  9. GENE MUTATIONS • A point mutation substitutes one nucleotide for another. GAT CTC GAT CAC Draw a picture: middle of p. 10

  10. Example of a point mutation • Sickle cell anemia

  11. 2) A frameshift mutationinserts or deletes a nucleotide in the DNA sequence. THE CAT ATE THE RAT • THC ATA TET HER AT…. Draw a picture: bottom of p. 10

  12. Example of a frame shift mutation: • Tay–Sachs disease • Develops @ around 6 months of age • Nerves start deteriorating • Child becomes blind, deaf, and unable to swallow • Death usually occurs before the 4th year

  13. Chromosomal mutations • affect many genes • may occur during crossing over

  14. Mutations may or may not affect phenotype (looks). • Chromosomal mutations tend to have a big effect. • Some gene mutations change phenotype. Ex: down syndrome

  15. blockage no blockage • Some gene mutations do not affect phenotype. • A mutation may be silent. Ex: Cystic Fibrosis- caused by a deletion

  16. Mutations in body cellsdo not affect offspring. Ex: Lung cancer Skin cancer

  17. Mutations in sex cellscan be harmfulorbeneficial to offspring. • Natural selection often removes mutant alleles from a population

  18. CCR5 32 is a deletion thought to resist the bubonic and pneumonic plague as well as HIV Beneficial mutations Mutations that cause resistance to antibiotics

  19. Conjoined Twins • Chang and Eng Bunker • Born in 1811 • Married sisters • Had 21 children between them • In modern times, they could have easily been separated • Died on the same day in 1874 • Chang contracted Pneumonia and died in his sleep- Eng refused to be separated from his dead twin and died several hours later.

  20. Mutations caused by Mutagens • Radiation

  21. Mutations 2 (5m37s)

More Related