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A brief introduction to Research Methodology By

A brief introduction to Research Methodology By Dr.Shaikh Shaffi Ahamed Ph.d., Asst. Professor Dept. of Family & Community Medicine. What is Research?.

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A brief introduction to Research Methodology By

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  1. A brief introduction to Research Methodology By Dr.Shaikh Shaffi Ahamed Ph.d., Asst. Professor Dept. of Family & Community Medicine

  2. What is Research? A systematic investigation, involving thecollection of information (data), to solve aproblem or contribute to knowledge about a theory or practice.Research is critical in medicine because itleads to new discoveries and can changepeoples’ lives by improving health and well being. Research helps to provide scientificunderstanding and solves practical problems.

  3. Research (cont.) Relies on methods and principles that willproduce credible and verifiable results. All research starts with an idea or question based on personal experiences.

  4. Scientific Approach The most sophisticated method of acquiringknowledge is by scientific approach.Combines important features of inductionand deduction together with other methodsto create a system of acquiring knowledge.Generally more reliable than other methods.Approach used most often to performmedical research.

  5. Scientific research is an integrated approach of deduction and induction Deduction Hypothesis generation Known/unknown truths In sample population Universe Testing the hypothesis Induction (Inference on hypothesis) generalization of the results

  6. Aims of epidemiologic research Describe the health status of a population Explain the etiology of disease Predict the disease occurrence Control the disease distribution

  7. Definition of Epidemiology The study of the distribution and determinants of health-related states or events in specified population, and the application of this study to control of health problems. [source: Last (ed.) Dictionary of Epidemiology, 1995]

  8. Definition of Epidemiology Study: surveillance, observation, hypothesis testing, analytic research, and experiments. Distribution: analysis by time, place, and person. Determinants: physical, biological, social, cultural, and behavioral factors that influence health. Health-related states or events: diseases, causes of death, behavior, reactions to preventive regimens, and provision and use of health services.

  9. Epidemiology and Biostatistics Epidemiology: Study design and interpretation Biostatistics: Methods for analysis

  10. MODEL OF THE RELATIONSHIP BETWEEN DIFFERENT TYPES OF RESEARCH Epidemiological Biomedical Policy making, planning, Management evaluation Health systems research Statistical Behavioral Social & economic

  11. BCG vaccination is not effective. Why ? • BCG vaccination coverage is good but not effective • Immuno-microbiological factors Poor nutrition (low protein intake) Poor immune reaction (race-specific) Tubercle bacillus strains Atypical mycobacterial infection ---- BIOMEDICAL PROBLEMS • Technical factors Quality of BCG vaccine ---- BIOMEDICAL PROBLEMS (iii) Operational factors Storage and transport of vaccine Handling of vaccine after reconstitution Technique of vaccination Logistic support (supply of vaccine, vaccinating equipment) ----- HEALTH SYSTEMS RESEARCH

  12. (b) BCG vaccination coverage is poor (i) Operational factors Coverage and efficiency of local health services ---- HEALTH SYSTEMS RESEARCH (ii) Human factors Indifference of population toward immunization Fear of reaction and low level of confidence in BCG Decline in concern about tuberculosis ----- BEHAVIOURAL PROBLEMS

  13. Preventable Causes of Disease BEINGS Biological factors and Behavioral Factors Environmental factors Immunologic factors Nutritional factors Genetic factors Services, Social factors, and Spiritual factors [JF Jekel, Epidemiology, Biostatistics, and Preventive Medicine, 1996]

  14. Causal model of risk factors for CVD Morbidity and Mortality (Stroke, MI) Biological Risk Factors (Hypertension, Blood Lipids, Homocysteine) Genetic Risk Factors (Family History) Behavioral Risk Factors (Cigarette, Diet, Exercise) Environmental Factors (Socioeconomic Status, Work Environment)

  15. Clinical issues and questions in the practice of medicine IssueQuestion Normality/abnormality Is a person sick or well? What abnormalities are associated with having a disease ? Diagnosis How accurate are diagnostic tests or strategies used to find a disease ? FrequencyHow often does a disease occur ? Risk What factors are associated with an increased likelihood of disease ? PrognosisWhat are the consequences of having a disease ?

  16. Treatment How does treatment change the future course of a disease ? PreventionDoes intervention on people without disease keep disease from arising? Does early detection and treatment improve the course of disease ? Cause What conditions result in disease ? What are the pathogen tic mechanisms of disease ?

  17. Execution of Research: Conceptualizing the problem: Need Background & Rationale Formulating the Objectives Generating hypotheses Testing hypotheses Designing the Approach Research design Methods and Materials Target population Study population Methods of collection Analysis and Interpretation of results

  18. THERE ARE ONLY A HANDFUL OF WAYS TO DO A STUDY PROPELY BUT A THOUSAND WAYS TO DO IT WRONG --- Sackett (1986)

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