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http://www.aecom.yu.edu/home/biophysics/dept/Karen1.gif. Jakes’ Contribution. Working with the colicin fragment at the Rockefeller Institute Known to Steitz because of her previous work with one of Steitz’s colleagues at Yale. Advantages to Colicin
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http://www.aecom.yu.edu/home/biophysics/dept/Karen1.gif Jakes’ Contribution • Working with the colicin fragment at the Rockefeller Institute • Known to Steitz because of her previous work with one of Steitz’s colleagues at Yale
Advantages to Colicin Only one fragment, appropriate length and stability Previous research showed colicin/ribosomal binding Today: would more likely used RNAse H, but this was not present at the time http://www.ionchannels.org/pdb-image/3EIP.jpg