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Lysteria monocytogenes and Shigella flexerni use actin based motility to spread to other cells

Lysteria monocytogenes and Shigella flexerni use actin based motility to spread to other cells. -Cause diarrhea, vomiting, fever, and can lead to menningitis and spontaneous abortions -Causes death in immunocompromised people (children, elderly, AIDS patients)

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Lysteria monocytogenes and Shigella flexerni use actin based motility to spread to other cells

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  1. Lysteriamonocytogenesand Shigellaflexerni use actin based motility to spread to other cells -Cause diarrhea, vomiting, fever, and can lead to menningitis and spontaneous abortions -Causes death in immunocompromised people (children, elderly, AIDS patients) -Produce a protein that encourages production of actin filaments at the cell surface -Propels bacteria through the cytoplasm (Comet tails) -Rams into the cytoplasmic membrane and pushes through into the next cell -Avoids much of the immune system http://cmgm.stanford.edu/theriot/movies.htm#Hits Movies:

  2. Vibriofischeri and its host, the bobtail squid Close up of single bacterium (Vibrio) Bacteria (Vibrio) glowing on a petri dish Light organs on squid belly use Vibrio to reflect the same wavelength of light as the moon, hiding their shadow from preditors A squid that uses glowing bacteria to avoid being eaten (the glow from the bacteria mimics the moonlight so the squid can’t be seen from below-just looks like moonlight from below)

  3. Vibrioand its host, the Pineapple fish Pineapple fish-lower jaw contains a photophore where Vibrio reside. The bioluminescence attracts zooplankton. -glows orange during the day, blue green by night.

  4. The angler fish uses bioluminescent bacteria to attract prey

  5. Quorum sensing in Vibrio http://subrealism.blogspot.com/2009_04_01_archive.html Bioluminescence is very expensive so the cells only want to bioluminesce when other cells are around. No point if they’re not in the squid light organ.

  6. The amazing Myxococcusxanthus

  7. Myxococcus Myxococcusxanthus cell A Myxococcusswarm

  8. Aggregation and “rippling” of Myxococcus

  9. Fruiting bodies Myxococcusfruiting bodies Dictyostellumdiscoideum-slime mold fruiting bodies (amoeba)

  10. Slime mold fruiting bodies Dictyostellumdiscoideum-slime mold fruiting bodies (amoeba)

  11. Sporulation sites on the surfaces of WT colonies. Bacillus fruiting bodies Bacillus fruiting body. A sporulation gene was fused with lacZ and the cells were plated on medium containing x-gal. You can see the where sporulation occurs by the dark blue color Branda S S et al. PNAS 2001;98:11621-11626

  12. Movies http://www.youtube.com/watch?v=oVGEFGzS7Wo&feature=related http://www.youtube.com/watch?v=O1jPzhz1Qyc http://www.youtube.com/watch?v=bkVhLJLG7ug&feature=related

  13. Healthy ant

  14. Zombie ants

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