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a. b. 120. T47D. 100. 80. % Cell migration. 60. *. 40. 20. 0. Vector. S100A7. SCP6. % Cell migration. *. Supplementary Fig. 1. T47D. 30. Vector S100A7. 20. % Invasion. *. 10. *. 0. -EGF +EGF. Supplementary Fig. 2. EGF. EGFR. LIMK-1/2.
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a b 120 T47D 100 80 % Cell migration 60 * 40 20 0 Vector S100A7 SCP6 % Cell migration * Supplementary Fig. 1
T47D 30 Vector S100A7 20 % Invasion * 10 * 0 -EGF +EGF Supplementary Fig. 2
EGF EGFR LIMK-1/2 Active Rac-1 GTP S100A7-ERα- Migration p-Cofilin F-actin G-actin N p-p65-NF-KB ATP NF-KB binding site S100A7-ERα+ MMP-9 Invasion LIMK-1/2 MMP-9 Active Rac-1 MMP-9 Invasion Migration Supplementary Fig. 3