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Amino Acid Supplementation during Endurance Exercise

Amino Acid Supplementation during Endurance Exercise. Dustin Joubert. Take Home Message. Should endurance athletes consume Amino Acids during exercise? No Unless… 1) Carbohydrate is unavailable 2) You are taking the 5 th grade exit exam afterwards. The Claims. Decrease central fatigue

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Amino Acid Supplementation during Endurance Exercise

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  1. Amino Acid Supplementation during Endurance Exercise Dustin Joubert

  2. Take Home Message • Should endurance athletes consume Amino Acids during exercise? No • Unless… 1) Carbohydrate is unavailable 2) You are taking the 5th grade exit exam afterwards

  3. The Claims • Decrease central fatigue • Inhibit muscle tissue breakdown • Slow lactic acid build-up

  4. Decrease central fatigue?

  5. Evidence – BCAAs & Central Fatigue • Theoretical mechanisms • Multiple parts, established animal models • Human studies less conclusive • BCAA supplementation • Beneficial if glycogen depleted, no carbohydrate • No effect when carbohydrate included • Except on post-test cognitive function (Hassmen, 1994) Bloomstrand (2001). Amino acids and central fatigue. Amino Acids. Blomstrand (2006). A role for branched-chain amino acids in reducing central fatigue. The Journal of Nutrition.

  6. Inhibit muscle tissue breakdown?

  7. Evidence – Muscle Damage • Attenuated ↑ in creatinekinase/lactate dehydrogenase(Coombes, 2000) • 2 groups, 120 min cycling at 70% VO2max • 14d BCAA supplementation (7d before, 7d after) • Reduced CK/LDH from 2-hr to 5-d post-exercise • Controlled for normal dietary protein intake • No effect on ↑ in CK, performance, soreness (Knecthle, 2011) • 2 groups, 100 km ultra-marathon • Pre/during supplementation • Only compared pre-post samples • No Placebos

  8. Slow Lactic Acid production?

  9. Evidence – Lactic Acid Production • Incremental cycling to exhaustion (Matsumoto, 2009) • Methods • BCAA vs. iso-caloric carbohydrate drink • 1 wk/pre-exercise supplementation • Randomized, double-blind, cross-over design • Results • No change in maximal exercise time or workload • No change in blood lactate at any workload • Increase in VO2max with BCAA • Lactate threshold higher workload, VO2, %VO2 w/BCAA • Meaningful?

  10. Take Home Message • Should endurance athletes consume Amino Acids during exercise? No • Unless… 1) Carbohydrate is unavailable 2) You are taking the 5th grade exit exam afterwards

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