1 / 22

PET – POSITRON EMISSION TOMOGRAPHY

PET – POSITRON EMISSION TOMOGRAPHY. PET: POSITRON EMISSION TOMOGRAPHY. Most used PET radiotracers. Unstable nucleus. positron antiparticle of the electron (same charge, opposite semn). electron. positronium. 2 gamma photons, 511 keV. Coincidence detection (interval 10 -9 sec.).

olinda
Download Presentation

PET – POSITRON EMISSION TOMOGRAPHY

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. PET –POSITRON EMISSION TOMOGRAPHY

  2. PET: POSITRON EMISSION TOMOGRAPHY

  3. Most used PET radiotracers

  4. Unstable nucleus positron antiparticle of the electron (same charge, opposite semn) electron positronium 2 gamma photons, 511 keV Coincidence detection (interval 10-9 sec.) • detector: • Bi germanat crystal(BGO) • Photomultipliers around PET principle

  5. Anihilation process Anihilation photon g Anihilation electron/positron b- b+ Anihilation photon g Desintegration through positron emission Device

  6. PET: analogs metabolic Glucidic Metabolism Glicolisys in malignant cell The germinating idea of PET: Nobel Prize Medicine Laureat, Dr. Otto Warburg: <The prime cause of cancer is the replacement of the respiration of oxygen by normal body cells by a fermentation of sugar>

  7. GLUT transporters GLUT8 GLUT6

  8. 18FFDG (18F-2fluoro-2deoxi-Dglucose)

  9. PET Indication • Miocardial Scintigraphy • Tumoral Scintigraphy : • pulmonar neoplasm • mamary neoplasm • cerebral neoplasm • ovarian • gastrointestinal neoplasia • limphoma • Head-neck tumors • endocrin tumors : thyroidian, carcinoid, pheocromocitoma

  10. Normal 18FFDG PET image

  11. Normal PET and PET-CT images

  12. Pathologic 18F FDG PET images in cancer

  13. Lung cancer

  14. Lung cancer with metastases

  15. Hodgkin lymphoma with metastases

  16. Melanoma

  17. PET-CT images

  18. Imagini PET (18FFDG), CT şi PET-CT normale (secţiuni coronale) PET PET - CT CT

  19. PET + CT = PET-CT

More Related