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CHAPTER 8B REVIEW. MITOSIS a. 2n to 2n (diploid to diploid) b. forms cells identical to parent cell. MEIOSIS a. 2n to n (diploid to haploid) b. forms cells different from parent cell. ESSAY #1. MITOSIS c. 1 divison d. forms 2 daughter cells e. makes somatic cells. MEIOSIS
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MITOSIS a. 2n to 2n (diploid to diploid) b. forms cells identical to parent cell MEIOSIS a. 2n to n (diploid to haploid) b. forms cells different from parent cell ESSAY #1
MITOSIS c. 1 divison d. forms 2 daughter cells e. makes somatic cells MEIOSIS c. 2 divisions d. forms 4 daughter cells e. makes sex cells ESSAY #1 (cont.)
ESSAY #2 • HOW IS A KARYOTYPE MADE? • A. Blood is separated with a centrifuge (fluid plasma on top and cells on bottom) • B. A hypotonic solution is added to break the cell membrane of the RBC
C. White blood cells are used • D. Cells stopped in metaphase with colchicine • E. Arranged by size, shape, bars matching
ESSAY #3 • Each of the disorders is a 5 point essay: • DOWN SYNDROME- • 1. round face • 2. small teeth • 3. flat bridge on nose • 4. mentally challenged • 5. susceptible to respiratory problems, Alzheimers • Trisomy 21 • Short stature
ESSAY #3 • KLINEFELTER’S SYNDROME (do 5) • A. small testes • B. infertile (cannot bear children) • C. breast development • D. rounded hips • E. XXY (you may only use one of the chromosome letters) • F. poor beard growth
ESSAY #3 • TURNER SYNDROME • A. small ovaries • B. infertile (cannot bear children) • C. web of skin between head and shoulders • D. poor breast development • E. XO • F. short stature
1. Somatic or Sex Cell? • Skin • Somatic • Sperm • Sex • Blood • Somatic • Egg • sex
2. Difference between… • Sex chromosomes and autosomes? • ANSWER: Sex chromosomes are X and Y (usually #23) Autosomes are rest of chromosomes, in human karyotype #1-22
3. What is the difference… • Between diploid and haploid (and symbols)? • ANSWER:Diploid is 2n with 2 sets of chromosomes in a cell • Haploid is n with one set of chromosmes in a cell
#4 • What are homologous chromosomes? • ANSWER: two sister chromatids from the father and two sister chromatids from the mother with the same inherited characteristics
#5 • What is the diploid and the haploid number for humans? • ANSWER: diploid – 2n = 46 • haploid – n = 23
#6 Karyotypes: Which is it? • Klinefelter’s • Turner’s • Normal Male • Normal Female • Normal Female • Due to XX
Which does not belong? • Skin cell • Diploid • Gamete • Somatic cell • ANSWER: gamete
Which does not belong? • 2N • Haploid • Gamete • Sperm • Egg • ANSWER: 2N
6. Which is not a male? • XXY • XY • XO • XXXY • Which is the normal male? • XO is not a male and XY is the normal male
7. Which phase lasts the longest? • Prophase I • Metaphase I • Prophase II • Metaphase II • Prophase I (Think!! a lot goes on here)
Meiosis or Mitosis? • Makes cells that are haploid? • Meiosis • Makes cells that are diploid? • Mitosis • Makes sex cells • meiosis
What is the difference between • A gamete and a zygote? • A gamete is a sex cell (like egg and sperm) and a zygote if a fertilized egg (the joining of egg and sperm)
8. And 10.How are they related? • Tetrad and synapsis • Tetrad are 4 homologous chromosomes and synapsis is the joining of these 4 to form a tetrad
8. In what phase… • Does synapsis (joining of tetrads) form? • Prophase I • Prophase II • Metaphase I • Metaphase II • ANSWER: Prophase 1
9. Crossover • When does it occur? • During prophase I • Between which two chromosomes does it occur? • Inner two of a tetrad • What is the site where it occurs? • chiasma
11. What is a chiasma? A B C
11. CHIASMA ANSWER Point where crossing over occurs between two inner chromosomes
12.Hair color • Is a gene on a chromosome. The variations of it, such as brown, red, or black would be known as _________. • Alleles are the choices of a gene
13. + 23. How many possible combinations? • What is the formula? • 2n • What does n stand for? • Haploid number • How many combos if n = 2? • 4
13. (cont.) How many possible combinations? • How many combos if n = 3? • 8 = (2 x 2 x 2) • How many combos if n = 23? • About 8 million
14. Karyotypes: Which is it? • Klinefelter’s • Turner’s • Normal Male • Normal Female • ANSWER: Turner’s
14. Karyotypes: Which is it? • Klinefelter’s • Turner’s • Normal Male • Normal Female • ANSWER: Normal Male
14. Karyotypes: Which is it? • Klinefelter’s • Turner’s • Normal Male • Normal Female • ANSWER: Klinefelter’s
Name the disorder: • XO • Turner’s syndrome • XXXY • Klinefelter’s syndrome • Trisomy 21 • Down Syndrome
15.What type of mutation? • Duplication • Insertion • Deletion • Translocation • Inversion • Duplication
15. What type of mutation? • Insertion • Deletion • Translocation • Inversion • Deletion
15. What type of mutation? • Insertion • Deletion • Translocation • Inversion • Inversion
15. What type of mutation? • Insertion • Deletion • Translocation • Inversion • Translocation
Just Checking: What is this showing? • Crossing over • It occurs during what phase? • Prophase I
16. What is CML? • A cancer caused by the translocation of chromosome _________ and ________. • 9 and 22
In case you wondered…CML • Also called: The Philadelphia Chromosome (Ph1) • Chronic Myelogenous Leukemia
17. If the testicle cell has • 50 chromosomes, how many chromosomes does the sperm have?100 50 25 10 • ANSWER: 25
18. What are the chances? • That a female with Down Syndrome will have a child with Down Syndrome?100% 75% 50% 25% 0% • ANSWER: 50%
If the Diploid Number is… 46 18 72 Then the Hapoid Number is… 23 9 36 Give the missing info
19. Which part of Meiosis… • Is like mitosis (except it has two cells)? • Meiosis I • Meiosis II • ANSWER: Meiosis II
21. Who determines… • The sex of the offspring? Father or mother • FATHER • WHY? • If he donates an X = child is girl (XX) • If he donates a Y = child is a boy (XY) • Mother only can donate an X
22. Define: • Karyotype: • A. diagram of meiosis • B. An orderly display of magnified images of the individual chromosomes • C. chromosomes as they appear in Prophase I • ANSWER: B
23. Define… • Nondisjunction: • A. switching of parts of two chromosomes • B. inversion of two parts of a chromosome • C. members of chromosome pairs fail to separate • D. You Diss Yo Homey • ANSWER: C
What are the two gametes of humans? • A. egg and sperm • B. X and Y • C. ovaries and testes • D. Klinefelter’s and Turner’s • ANSWER: A
In which phase of Meiosis? • Do the tetrads form? • Prophase I • Are 4 haploid cells formed? • Telophase II
Which phase of Meiosis? • Do you know? • How many cells? • Is it Meiosis I or II? • PROPHASE II
Which phase of meiosis? • Where are the centrioles? • Where are the tetrads? • Metaphase I