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AND (10nM) RAD (0.6nM) LET (50nM)

Fig 2. MCF7-AROM1 (ER+ HER2-). A. B. p=2.4 x 10 -5. p=2.2 x 10 -5. p=0.035. Fold change in cell number relative to control. Fold change in cell number relative to control. p=1.3 x 10 -5. AND (10nM) RAD (0.6nM) 4-OHT (5nM) . AND (10nM) RAD (0.6nM) LET (50nM) .

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AND (10nM) RAD (0.6nM) LET (50nM)

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  1. Fig 2 MCF7-AROM1 (ER+ HER2-) A B p=2.4 x 10-5 p=2.2 x 10-5 p=0.035 Fold change in cell number relative to control Fold change in cell number relative to control p=1.3 x 10-5 AND (10nM) RAD (0.6nM) 4-OHT (5nM) AND (10nM) RAD (0.6nM) LET (50nM) BT474-AROM3(ER+/HER2 amp) C D p=0.02 p=0.0008 p=0.002 Fold change in cell number relative to control Fold change in cell number relative to control AND (10nM) RAD (0.6nM) 4-OHT (25nM) AND (10nM) RAD (0.6nM) LET (25nM) E LTED (ER++HER2++) + + + + + + + + + + + + + + + + + + + + p=7.8 x 10-6 + + + + + + + + + + - - - - - - - - - - Fold change in cell number relative to control + + - + + + + - - - - - - - - + + - + + p=0.0001 E2 (0.01nM) RAD (0.6nM) 4-OHT (10nM)

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