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APPLICATION TO THE HADROTHERAPY FOR OCULAR MELANOMAS

APPLICATION TO THE HADROTHERAPY FOR OCULAR MELANOMAS. G.A. Pablo Cirrone Qualified Medical Physicist and PhD Student University of Catania and Laboratori Nazionali del Sud INFN, Italy.

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APPLICATION TO THE HADROTHERAPY FOR OCULAR MELANOMAS

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  1. APPLICATION TO THE HADROTHERAPY FOR OCULAR MELANOMAS G.A. Pablo Cirrone Qualified Medical Physicist and PhD Student University of Catania and Laboratori Nazionali del SudINFN, Italy

  2. LNS Superconducting Cyclotron in Catania is the unique machine in in Italy and South Europe used for protontherapy

  3. Depth doses in radiotherapy: single fields

  4. Why clinical proton beams? • penetration depth is well-defined and adjustable • most energy at end-of -range • protons travel instraight lines • dose tonormal tissueminimised • no dose beyond target

  5. MEDICAL APPLICATION OF THE CATANA FACILITY • Choroidal Melanoma • 85 - 90 % successfully treating with proton beams • About 300 new cases for year in Italy • In the world 5000 patients have been already treated with proton beams • Age related subfoveal macular degenerations with subretinal neovascular membrane • This is the main cause of third age blindness in EC countries • It is a “social disease” for EC INFN - LNS

  6. PRESENT TREATMENT ROOM • 0 ° respect the switching magnet • 80 meter after extraction • 3 m proton beam line LAYOUT OF LNS

  7. Modulator & Range shifter Ligth field Scattering system Monitor chambers Laser

  8. Patient ready for treatment

  9. 2 mm Sensible Volume = 0.05 cm3 DETECTORS USED FOR DOSE DISTRIBUTION MEASUREMENTS DEPTH DOSE DISTRIBUTION LATERAL DOSE DISTRIBUTION • Markus Ionization chamber • Silicon diode • GAF Chromic Film • Thermoluminescent dosimeters Markus Chamber layout Irradiated GAF Chromic Risolution 100 m for DDP and 200 m for LDP

  10. ‘PURE’ BRAGG PEAK EXPERIMENTAL RESULTS

  11. MODULATED BRAGG PEAK

  12. EXPERIMENTAL LATERAL DOSE DISTRIBUTION

  13. Geant4 applications in prothon therapyour goals • Three dimensions dose distribution verification in water at isocenter in the treatment conditions Comparison with experimental and treatment planning data • Simulation, design and realization of critical elements of a proton beam line • Scattering system • Modulation system • Collimators along the beam line

  14. Proton therapy group in Catania • G. Cuttone Project Leader INFN • G.A.P. Cirrone Qualified Medical Physicist and PhD student • V. Salamone • L. Raffaele • M.G. Sabini • L. Valastro • P. Lojacono • V. Patti Qualified Medical Physicist Student for Medical Physics Qualification

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