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Non-commercial cultures (MODS, NRA, CRI). Liquid culture & DST. Rapid speciation. LED microscopy and same-day diagnosis. Automated NAAT – Xpert MTB/RIF (detection & DST). New SS+ case definition. 2-specimen approaches. First Referral Level. 10-40%. Rapid colorimetric DST.
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Non-commercial cultures (MODS, NRA, CRI) Liquid culture & DST Rapid speciation LED microscopy and same-day diagnosis Automated NAAT – Xpert MTB/RIF (detection & DST) New SS+ case definition. 2-specimen approaches First Referral Level 10-40% Rapid colorimetric DST Manual NAAT (detection)** LPAs* 70% Peripheral Lab Distance from Patients % Access after 5 years POC test (detection) Predictive LTBI Manual NAAT (detection) *** Community Health Care 95% 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Abbreviations DST: Drug Susceptibility Test NAAT: Nucleic Acid Amplification Test LTBI: Latent TB Infection POC: Point of Care MODS: Microscopic observation drug-susceptibility NRA: Nitrate reductase assay CRI: Colorimetric redox indicator assay LED: Light-emitting diode LPA: Line probe assay * Manual NAAT: technology for MTB Drug Susceptibility Testing * * Manual NAAT: technology for MTB detection at the Peripheral Lab * * * Manual NAAT: technology for MTB detection at the Community Health Care Level Technologies in boxes: endorsed by WHO