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University of California, Irvine Brain Imaging Center (BIC). Site PI: Steven G. Potkin, M.D. (http://www.bic.uci.edu). BIC / NAMIC Synergy. Provide multi-modal datasets (structure and function MRI, genetic, cognitive, behavioral)
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University of California, IrvineBrain Imaging Center (BIC) Site PI: Steven G. Potkin, M.D.
BIC / NAMIC Synergy • Provide multi-modal datasets (structure and function MRI, genetic, cognitive, behavioral) • Provide neuroanatomical expertise into the development of automated algorithms • For DTI • For regional and structural parcellation • Genetic expertise • Statistical methods development
Participants Postdocs and Students: • Seyoung Kim • Vid Petrovic • Martina Panzenboeck • David Medina Fuentes • Zhiyu He • Liv Trondsen Investigators: • Steven G. Potkin • James H. Fallon • Padhraic J. Smyth • David B. Keator • Jessica A. Turner • Hal S. Stern • Falko Kuester • Yi Jin
Brain Imaging Center’s capabilities • Brain Imaging Center • HRRTOne of 5 high resolution PET scanners in the US • Cyclotron & radiopharmaceuticals: ligand development • Biomedical Informatics Research Network - BIRN: A 5 year, NIH funded project to develop multi-site structural and functional MRI techniques • Transdisciplinary Imaging Genetics Center:Developing imaging genetics, combining an individual’s genetic background, brain imaging and treatment response; NIH funded center • NAMIC, ADNI, Optiputer/Cal-IT(2) • Current Industry Imaging Collaborations: Allergan, Aventis, BMS, Forest, Novartis, Organon, Pfizer 2.0mm
Neurogenetics Group, University of Toronto NAMIC participants labelled Sajid Shaikh Natalia Potapova Rudi Hwang Livia Martucci Gwyneth Zai Claudia Rothe Dan Muller Jim Kennedy Centre for Addiction and Mental Health (CAMH) * A Voineskos not shown.
EXTRACTING DATA FOR ANALYSIS Data are returned in a format suitable for association-type studies (m-link or case-control). Additional formats may be designed as needed (such as vertical haplotypes {} ). Data may be transcribed and converted to document formats supported by the analysis program (tab de-limited text, etc…). 1 2 2 1 1 2 2 2 2 1 1 1 2 2 1 1 With access to source codes, or by invoking special features in downstream applications, the database can include automated running of analyses or transfer of data to other spreadsheets/databases.