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Inflammation and repair

Inflammation and repair. Dr Shaesta Naseem 1-10-11. Gross and histopathology. 1- Fibrinous pericarditis. Organ: Pericardium Dx : Fibrinous Inflammation . ACUTE FIBRINOUS PERICARDITIS. Fibrinous Pericarditis : Section of Heart shows:.

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Inflammation and repair

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  1. Inflammation and repair Dr ShaestaNaseem 1-10-11

  2. Gross and histopathology

  3. 1- Fibrinouspericarditis

  4. Organ: Pericardium Dx: Fibrinous Inflammation

  5. ACUTE FIBRINOUS PERICARDITIS

  6. FibrinousPericarditis: Section of Heart shows: • The pericardium is distorted by thick irregular layer of pinkish fibrinous exudate with some red cells and inflammatory cells. • The subpericardial layer is thickened by edema and shows dilated blood vessels, chronic inflammatory cells.

  7. 2- Acute appendicitis

  8. ACUTE APPENDICITIS

  9. ACUTE APPENDICITIS

  10. ACUTE APPENDICITIS

  11. Acute Suppurative appendicitis:Cross Section of Appendix shows: • Accumulation of inflammatory exudate and pus cells in the lumen and the mucosa is ulcerated. • All layers of the appendix wall show edema, dilated and congested blood vessels and infiltration by many neutrophils. • Fibrino-purulent exudate is present on the serosal surface.

  12. 3-Skin pilonidal sinus

  13. FOREIGN BODY REACTION (PILONIDAL SINUS)

  14. FOREIGN BODY REACTION (PILONIDAL SINUS)

  15. Foreign Body reaction (Pilonidal sinus):Section of Skin Shows: • A sinus tract lined by an inflammatory granulation tissue in the dermis . • The lumen of sinus and wall contain large number of hair shafts with foreign body giant cells, lymphocytes , macrophages & neutrophils.

  16. 4-Chronic cholecystitis with stones

  17. 5-Bronchiectasis

  18. 6- Brain abscess

  19. 7- Pyemic abscesses of the kidney

  20. 8- Granulation tissue

  21. GRANULATION TISSUE

  22. GRANULATION TISSUE

  23. Granulation Tissue:Section of fragments of edematous, loose connective tissue shows: • Many small newly formed capillaries lined by plump endothelial cells. • Proliferation of fibroblasts is seen. • Inflammatory cells including macrophages, lymphocytes, plasma cells and neutrophils in the oedematous stroma. • Pink homogenous collagen fibres may be identified.

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