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RESPIRATION & OXIDATION

RESPIRATION & OXIDATION. GLYCOLYSIS. Step 1: Phosphorylation: Glucose + 2ATP  Fructose 1,6-diphosphate + 2ADP Step 2: Splitting 6C sugar to 2 x 3C sugars: Fructose 1,6-diphosphate  2 Glyceraldehyde Phosphate Step 3: Energy release:

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RESPIRATION & OXIDATION

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  1. RESPIRATION & OXIDATION

  2. GLYCOLYSIS • Step 1: Phosphorylation: Glucose + 2ATP Fructose 1,6-diphosphate + 2ADP • Step 2: Splitting 6C sugar to 2 x 3C sugars: Fructose 1,6-diphosphate  2 Glyceraldehyde Phosphate • Step 3: Energy release: 2 Glyceraldehyde Phosphate  2 Pyruvate (oxypropanoate) 8ATP 8ADP © 2010 Paul Billiet ODWS

  3. KREB'S CYCLE Enzymes located in the inner matrix of mitochondria (in eukaryotes) Note: Number of mitochondria per cell = activity of the cell On average 1000 per cell (between 20 and 10 000) © 2010 Paul Billiet ODWS

  4. Inner matrix Cristae Inter membrane space outer membrane Mitochondrial envelope inner membrane Image credit: Mitochondria

  5. Also produced from fatty acids and amino acids 3ADP 3ATP Step 1: Synthesising ACETYL COENZYME A Pyruvate  Acetyl CoA + CO2 (3C) (2C) (1C) CYTOPLASM  MITOCHONDRIA © 2010 Paul Billiet ODWS

  6. Acetyl CoA + Oxaloacetate Citrate + CoA (2C) (4C) (6C) KREB'S CYCLE 12ATP 12ADP Step 2: Oxidising Acetyl CoA back to the cytoplasm Breathed out or used by chloroplasts 2CO2 4 x 1/2O2 4H2O © 2010 Paul Billiet ODWS

  7. The Kreb's Cycle was discovered by using inhibitors and isolating enzymes from tissues rich in mitochondria • Total ATP from 1 molecule of glucose in AEROBIC CONDITIONS • Glycolysis - 2 (phosphorylation) +8 Kreb's Cycle +30 (2x15) TOTAL 36 ATP © 2010 Paul Billiet ODWS

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