1 / 1

Design of a Selective, Photo- Activatable de Novo Protein

Design of a Selective, Photo- Activatable de Novo Protein. H. Christopher Fry, Andreas Lehmann, Jeffery G. Saven, William F. DeGrado and Michael J. Therien NSEC DMR08-32802.

rance
Download Presentation

Design of a Selective, Photo- Activatable de Novo Protein

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Design of a Selective, Photo-Activatable de Novo Protein H. Christopher Fry, Andreas Lehmann, Jeffery G. Saven, William F. DeGrado and Michael J. Therien NSEC DMR08-32802 First example of a computationally de novo designed protein that binds selectively an emissive abiological chromohore. Design of de novo proteins that bind abiological cofactors provide a general strategy to build proteins that possess functions not seen in nature. In designed protein complexes containing abiological Zn-porphyrin cofactors, electron and energy transfer reactions can be light activated and novel nonlinear optical and photophysical properties can be controlled.

More Related